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Date/Time:  11/23/18 6:34 GMT
 

Aldolase Activity Colorimetric Assay Kit

Aldolase (Fructose-Bisphosphate Aldolase: EC 4.1.2.13) is an important
enzyme for both glycolysis and gluconeogenesis. It catalyzes the reversible
reaction of fructose-1,6-bisphosphate to glyceraldehyde-3-phosphate &
dihydroxyacetone. There are 2 classes of Aldolase-class l: found in animal
and plant tissues and class II: found in prokaryotes and lower eukaryotes.
Class I Aldolase has 3 isozymes-Type A: found in muscle and red blood
cells, Type B: found in liver and kidney and Type C: found in brain.
Aldolase A deficiency leads to myopathy & hemolytic anemia. Muscle disease
and liver injury can also cause increased serum aldolase. Accurate
detection of aldolase activity is valuable for diagnostic and mechanistic
studies. In Aldolase Activity Assay, aldolase converts fructose-1,6-
bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone, and
through a series of reactions, reduces a nearly colorless probe to a
colored product with absorbance at 450 nm. This assay kit is simple,
sensitive, and high-throughput adaptable. Detection limit: less than 0.1 mU
of aldolase activity in a variety of samples.

https://www.creativebiomart.net/al , dolase-activity-colorimetric-assay-kit-
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Aldolase Activity Colorimetric Assay Kit
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