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Contact: Juanna Chan
Company: Suzhou Myland Pharm & Nutrition Inc.
No# 262 Dongping St. SIP Suzhou CN.
Suzhou 215123
China
Phone: +8651266702819
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Date/Time:  6/19/23 1:36 GMT
 

7,8-Dihydroxyflavone CAS No.:38183-03-8 98.0% purity min. for promoting int

Product name:7,8-Dihydroxyflavone
Other name :7,8-DIHYDROXYFLAVONE;
7,8-dihydroxy-2-phenyl-4 , -benzopyrone;
DIHYDROXYFLAVONE, 7,8-(RG);
7,8-Dihydroxyflavone hydrate;
7,8-dihydroxy-2-phenyl-1-benzopyran-4- , one
CAS No.:38183-03-8
Molecular formula:C15H10O4
Molecular weight:254.24
Purity:98.0%
Appearance :Yellow powder
Application:Dietary Supplement Raw Material
3.Product introduction
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring member of the flavonoid
family. Studies have shown that 7,8-DHF can cross the blood-brain barrier,
effectively mimic brain derived neurotrophin (BDNF), specifically bind to TrkB
receptor, thus inducing dimerization and autophosphorylation of TrkB, and further
activating MAPK/ERK, PI3K/Akt and PC downstream of the receptor γ Three signal
pathways. At present, 7,8-DHF has been applied to the prevention and treatment of
various BDNF/TrkB signaling related diseases, and has achieved a series of exciting
results.
4.Features
(1) High purity: 7,8-Dihydroxyflavone preparation can obtain high-purity products
through natural extraction and fine manufacturing process. High purity means better
bioavailability and fewer adverse reactions.
(2) Safety: 7,8-Dihydroxyflavone is a natural product that has been proven to be
safe to humans. Within the dosage range, it has no toxicity or side effects.
(3) Stability: 7,8-Dihydroxyflavone preparation has good stability and can
maintain its activity and effect under different environmental and storage
conditions.
(4) Easy to absorb: 7,8-Dihydroxyflavone preparation can be quickly absorbed by
the human body, enter the blood circulation through the intestinal tract, and
distribute to different tissues and organs.
5.Applications
7, 8-DHF, as an effective small molecule activator of TrkB receptor, can play the
role of neuron protection, neuron regeneration, synaptic plasticity regulation,
etc. by simulating BDNF specific binding to TrkB and activating downstream signal
pathways, so as to significantly improve the symptoms of emotional learning and
spatial memory decline, cognitive ability decline, motor function decline and other
symptoms of nervous system disease such as Alzheimer's disease or aging animal
models, And alleviate the related phenotypes of mental illness and obese animals.
Meanwhile, so far, no significant toxic side effects of 7,8-DHF have been found in
experimental animals. 7,8-DHF has great potential and value in the prevention and
treatment of BDNF/TrkB related issues.

Minimum Order: 1 bags

7,8-Dihydroxyflavone CAS No.:38183-03-8 98.0% purity min. for promoting int
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