Cotinine (COT) Rapid Tests

Cotinine (COT) Rapid Tests
The COT Rapid Test is a rapid chromatographic immunoassay for the detection of
Cotinine in human urine/saliva. This test will detect other related compounds,
please refer to the Analytical Specificity table in this package insert.

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that
produces stimulation of the autonomic ganglia and central nervous system when
in humans. Nicotine is a drug to which virtually every member of a tobacco-
smoking society is exposed whether through direct contact or second-hand
inhalation. In addition to tobacco, nicotine is also commercially available as
the active ingredient in smoking replacement therapies such as nicotine gum,
transdermal patches and nasal sprays. In a 24-hour urine, approximately 5% of a
nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as
hydroxycotinine; the concentrations of other metabolites are believed to
account for less than 5%.1 While cotinine is thought to be an inactive
metabolite, it's elimination profile is more stable than that of nicotine which
is largely urine pH dependent. As a result, cotinine is considered a good
biological marker for determining nicotine use. The plasma half-life of
nicotine is approximately 60 minutes following inhalation or parenteral
administration. 2 Nicotine and cotinine are rapidly eliminated by the kidney;
the window of detection for cotinine in urine at a cutoff level of 500 ng/mL is
expected to be up to 2-3 days after nicotine use. Well Biotect is an Alcohol
Rapid Tests Company.
More products view: https://www.wellbioscience.com/drugs-of-abuse/alco , hol-
rapid-tests.html

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