Etoxazole Intermediates Pharma 98% CAS No. 153233-91-1

Product Description
Etoxazole Intermediates Pharma With CAS No. 153233-91-1



Etoxazole has a mammalian toxicity LD50 of 5 g/kg and an environmental
persistence DT50 of 19 days.Toxicity towards fish is of potential concern.

Etoxazole was discovered in the 1980s by Yashima and was released for
commercial use in 1998 in Japan. It is sold under various commercial
preparations for crop application such as TetraSan 5 WDG and Zeal by Valent in
the United States.



Etoxazole is a new type of oxazole special acaricide newly developed by
Sumitomo Chemical. Patent number: EP0639572A1: Patent name: 2-(2,6-
DIFLUOROPHENYL)4-(2-ETHOXY-4-TERT-BUTYL , PHENYL)-2-OXAZOLINE: Patent application
date: 1992-04-28: Patentee: ASHIMA KAGAKU KOGYO KK kills harmful mites by
inhibiting the embryo formation of mite eggs and the molting process from
larvae to adult mites. It has contact killing and stomach toxicity, no systemic
properties, but it has strong chemicalbook penetration ability and is resistant
to rainwater. scour. Studies have shown that etoxazole has a strong killing
effect on the eggs and young nymphs of mites. It does not kill adult mites, but
it can significantly inhibit the hatching rate of female adult mites. pest
mite.


Etoxazole Intermediates Pharma 98% CAS No. 153233-91-1 0




ITEM CONTENT
Alias 2-(2,6-Difluorophenyl)-4-[2-ethoxy-4-(2-methyl-2-p , ropanyl)phenyl]-4,5-
dihydro-1,3-oxazole
Pur , ity 98%
Appearance colorless crystalline powder with a musty odor
EINECS No. 201-167-4
CAS No. 153233-91-1
Type intermediates for pharmaceuticals, pesticides and dyestuffs
Storage Sealed in dry,2-8°C
Boiling Point 449.1±45.0 °C(Predicted)
Molecular Formula C21H23F2NO2
Hazard statements H410
Melting Point 101-102°
WGK Germany 3
Solubility in water insoluble in H2O, slightly soluble in hexane, n-
heptane, soluble




Etoxazole Intermediates Pharma 98% CAS No. 153233-91-1 1













Toxicity

Acute oral LD50>5000mg/kg of etoxazole original drug in rats, acute
percutaneous LD50>2000mg/kg, acute inhalation LC50>1.09mg/L; no irritation to
rabbit eyes and skin; no sensitization to guinea pig skin; 90-day subchronic
feeding toxicity test in rats The maximum no-effect dose: 6.12 mg/kg·d for
male rats, 20.50 mg/kg·d for female rats; mutagenicity test: Ames test, mouse
bone marrow cell micronucleus ChemicalChemicalbookalbook test, lactation test
The results of the in vitro chromosomal aberration test of animal cells were
all negative, and no mutagenicity was found; the acute oral LD50>5000mg/kg,
acute percutaneous LD50>2000mg/kg, acute inhalation LC50> of etoxazole 110g/L
suspension in rats 1.09mg/L; slightly irritating to rabbit eyes and non-
irritating to rabbit skin; guinea pig skin sensitization test results showed no
sensitization. Ethoxazole original drug and 110 g/L suspending agent are low
toxicity acaricides.

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