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Company: Deren(Suzhou) Biotech Co.,ltd
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suzhou 215300
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Date/Time:  8/11/21 14:30 GMT
 

Licorice Root Extract Glabridin 40% 90% 98% for Skin Whitening

What is glabridin?

Glabridin, also known as Glycyrrhizic Flavone, is an kind of isoflavone. It
is extracted from the dried rhizome of Glycyrrhiza glabra L. Glabridin is
one of the main flavonoids in Glycyrrhiza glabra (accounting for 11%).
Numerous studies have shown that Glabridin can effectively inhibit the
activity of various enzymes during melanin production, especially inhibiting
tyrosinase activity. Moreover, it has other skin-care effect such as anti-
inflammation, anti-oxidation and sun-protection. It is a safe, mild and
effective whitening active ingredient. Only 100g Glabridin can be extracted
from 1000kg Glycyrrhiza glabra. Because of its complicated extraction
process, high cost and price, it is comparable to gold price. Therefore, it
is known as " Whitening Gold" in the world cosmetics industry. Glabridin has
attracted much attention and is widely used in skin beauty products and
cosmetics.

Product Name Glabridin
Part Used Root
Latin Name Glycyrrhiza uralensis Fisch
Extract Solvent Water&Ethanol
Appearance Light brown powder (White Powder for 90% 98%)
Assay(HPLC) ≥40% 90% 98%
Product Name Specification
Color
Glabridin 98% HPLC
White powder
90% HPLC
White powder
40% HPLC
White powder
40% HPLC
Brown powder

Function:
Skin whitening
as a natural whitening ingredient, the skin-whitening mechanism of Glabridin
mainly includes:
(1) inhibiting tyrosinase activity;
(2) inhibiting the activity of dopachrome tautomerase (TRP-2)
(3) inhibiting the activity of DHICA oxidase;
(4) exerting the function of endothelin antagonist;
(5) increasing the total antioxidant capacity of the skin;
(6) effectively scavenging oxygen free radicals and its chain reaction.
Moreover, through these synergistic effects, it effectively prevents the
polymerization of 5,6-dihydroxyindole (DHI) and the production ofdopachrome.
Thereby Glabridin can disturb and hinder the formation and transport of
melanin; and then it inhibits and reduces pigmentation so as to achieve
whitening skin effect.

Anti-inflammatory and antibacterial
the anti-inflammatory effect of Glabridin is related to its anti-oxidative
activity of scavenging reactive oxygen. Glabridin can inhibit the production
of NO in macrophages and the expression of inducible NO synthase. Then it
can prevent the development of inflammation. Also Glabridin can inhibit the
activity of staphylococcus aureus and candida albicans. It has a strong
antibacterial effect, and can be used for the treatment of acne.

Antioxidant
Glabridin has shown strong anti-free radical oxidation in the cytochrome
oxidation system. It can significantly inhibit the free radicals generated
in the body's metabolism. Then it prevents the oxidation-sensitive bio-
macromolecules (LDL, LDL, DNA) and cell walls from being oxidized and
damaged by free radicals. As an antioxidant, Glabridin can also inhibit the
production of reactive
Oxygen species and activation of p53; it regulates the cleavage of BCL-2 and
poly ADP ribose polymerase. and it can fight against oxygenated DNA
fragments of keratinocytes induced by UV; then it prevents sun-induced skin
aging.

Sunscreen
the conjugate property in the molecular structure of licorice flavonoids
assures that Glabridin is characterized by strong
Absorption of both ultraviolet and visible light. Therefore, the sunscreen
mechanism of Glabridin has the highest absorption peak for ultraviolet rays.
and it effectively blocks ultraviolet rays from the skin surface after being
applied to the skin.
Furthermore, it also works by absorbing unstable molecules of high-energy
ultraviolet rays. Then it converts the ultraviolet rays that damage the skin
into harmless, low-energy and non-damaging ones.

Application:
Skin care products: ointment, cream, lotion, facial mask
Bath products: shower gel
Hair care products: Shampoo, hair mask
Sunscreen products

Minimum Order: 25 kilograms

Licorice Root Extract Glabridin 40% 90% 98% for Skin Whitening
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