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Dimethicone/Dimethicone oil Dimethicone is a transparent colorless, odorless, odorless, non-toxic oily liquid. It has the characteristics of high flash point, low freezing point, good thermal stability and high and low temperature resistance. It can be used for a long time at -50°C to +180°C, and the temperature can reach 200°C if it is used in isolated air or in an inert gas for a long time. The surface silicon tension of the oil is small, the compressibility is large, the shear resistance is good, the viscosity-temperature coefficient is small, and the dielectric loss is small; it is resistant to electric isolation, corona, and non- flammable; it is hydrophobic and moisture-proof, and it also has good physiological inertia. Aplicatioin Dimethicone oil is widely used in electrical insulation, lubrication, shock and moisture resistance, defoaming, damping, heat carrier, hydraulic oil; it can be used as additives for paints and polishes. It can also be used as an additive for plastic processing to improve the mold release and wear resistance of plastics; daily chemical, medical use: Silicone oil is also an important component in the preparation of cosmetics and certain drugs.

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https://www.astersteroids.com/triple-receptor-agon , ist-peptides-retatrutide- ly-3437943-benefits-i , n-weight-loss/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Retatrutide, number LY-3437943, is arguably the latest promising drug for weight loss and the treatment of type 2 diabetes in obese/overweight patients. It has a completely new mode of action, and clinical trials have shown that it is more effective in weight loss than the FDA-approved Semagelutide(Wegovy) and Tirzepatide(Mounjaro). Perhaps you have not heard of this new weight loss peptide, today we will introduce it -Retatrutide. What is peptides Retatrutide LY-3437943? For sale Retatrutide LY-3437943 basic information: Cas No.:2381089-83-2 MF:C223H343F3N46O70 MW: 4845.444 Some approved weight loss products were originally developed to treat type 2 diabetes and work based on things like appetite control and delayed gastric empting. Retatrutide, a new drug in development for the treatment of obesity, is a triple receptor agonist that activates the GLP-1(glucagon-like peptide-1) receptor,GIP(Glucose-dependent insulin stimulating) receptor and GCGR (glucagon) receptors in the body, an unprecedented way to lose weight. How does Retatrutide lose weight? A preliminary understanding of how Retatrutide works for weight loss can be found in the three receptors it acts on. GLP-1: Glucagon-like peptide 1 GLP-1 is the key word in the treatment of type 2 diabetes, which mainly plays a role in regulating blood sugar in the body. it inhibits appetite and slows stomach emptying, helping to lower blood sugar while also helping with weight loss, which is why drugs used to treat type 2 diabetes can also be used for weight loss. GIP: Glucose-dependent insulin-promoting polypeptide GIP, also known as gastric inhibitory peptides, reduces hunger and increases satiety by reducing the secretion of stomach acid and the speed at which food is transported through the stomach. Compared with single GLP-1 agonists, GLP-1 and GIP dual agonists increase overall energy expenditure and reduce caloric intake, thus achieving better weight loss. This is the mode of action of Tirzepatide, a new type 2 diabetes drug developed by Eli Lilly and Co., which is a double receptor agonist for GLP-1 and GIP, and is a completely new attempt. Its effectiveness has been proven and it has been approved by the FDA. Tirzepatide’s weight loss was equally impressive, showing an average weight loss of 22.5 percent (about 52 pounds) after 72 weeks of use, while Semaglutide experienced an average weight loss of about 15 percent (34 pounds) after 68 weeks. Retatrutide is another Lilly innovation that has a completely new mode of action, activating GCG(glucagon) receptors in addition to GLP-1 receptors and GIP receptors.

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https://www.astersteroids.com/type-2-diabetes-trea , tment-semaglutide- wegovy- fda-approved-for- , heal , thy-weight-loss/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Peptides Semaglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist. Currently, we know that there are three products approved by the US FDA that contain semaglutide: Ozempic, Rybelsus and Wegovy. Among them, Ozempic and Rybelsus are mainly use for type 2 diabetes, and Wegovy(Semaglutide) use for weight loss. Details as below: What is GLP-1? GLP-1, or glucagon-like peptide-1, is a hormone that naturally producing in the body. It mainly produce in the gut. GLP-1 plays a crucial role in regulating blood sugar levels and appetite. In consuming food, GLP-1releasing into the blood, and it has several effects on the body. Stimulates insulin release: GLP-1 enhances insulin release. Insulin lowers blood sugar levels by encouraging glucose to enter cells. Inhibition of glucagon release: GLP-1 inhibits the release of glucagon, another hormone produced by the pancreas. Glucagon raises blood sugar levels by promoting the release of stored glucose in the liver. Slow gastric emptying: GLP-1 slows the rate at which the stomach dumps its contents into the intestines. This delay in gastric emptying helps reduce the rapid rise in blood sugar levels after a meal. Appetite suppression: GLP-1 acts on the brain to suppress appetite and promote satiety. Given these roles, GLP-1 plays a crucial role in regulating glucose metabolism in the body and promoting glucose control. Development of GLP-1 receptor agonists that can mimic the effects of GLP-1 to improve blood sugar control and weight loss in patients with type 2 diabetes or obesity. That’s what Semaglutide is like. How Semaglutide works? Peptides Semaglutide, first use to treat type 2 diabetes and obesity, acts as a GLP-1 receptor agonist by mimicking GLP-1 action. When inject Semaglutide, it binds to and activates GLP-1 receptors locating on various cells in the body, including pancreatic cells. By stimulating the release of insulin, glucose in the blood encourage to enter cells, thereby lowering blood sugar levels. Sugars that enter the cell also provide energy to the cell; By inhibiting glucagon, the liver does not produce excess glucose, thereby reducing blood sugar levels. By slowing stomach emptying, it reduces the rate at which nutrients, including glucose, are absorbed into the bloodstream, helping to control blood sugar spikes after meals. This effect prevents people from feeling hungry as soon as possible and does not produce the desire to eat, which helps people with type 2 diabetes or obesity control their appetite. Semaglutide also affects appetite regulation centers by acting on the brain, resulting in reduced hunger and increased feelings of gulping. Helps to control appetite and lose weight. Overall, Semaglutide helps improve blood sugar control in people with type 2 diabetes by increasing insulin release, inhibiting glucagon secretion, and slowing digestion, while having the effect of reducing weight control.

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https://www.astersteroids.com/tirzepatide-a-new-du , al-action-type-ii- diabetes-drug-showed-better- , weight-loss-results-than-semaglultide/ Purity:9 , 8% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Tirzepatide is a drug approved for medical use in the United States, European Union, Canada and Australia for the treatment and control of type 2 diabetes mellitus. As a dual GIP and GLP-1 receptor agonist, it is the first of its kind. What is Tirzepatide for Type 2 Diabetes? The incidence of type 2 diabetes has been on the rise worldwide in recent years, with about 420 million adults worldwide, 30 million people in the United States and 114 million people in China having type 2 diabetes. Globally, one person dies every six seconds from complications related to type 2 diabetes. Type 2 diabetes is the eighth leading cause of death in the world. Obesity and overweight are important risk factors for type 2 diabetes, and about 80-90% of type 2 diabetes patients are overweight or obese. Type 2 diabetes mellitus, also known as non-insulin-dependent diabetes mellitus, is a chronic metabolic disease characterize by pancreatic beta cell dysfunction and insulin resistance. Treatment for this disease focuses on controlling blood sugar, improving insulin resistance and protecting pancreatic beta cell function. The main methods are insulin therapy, oral hypoglycemic drugs, diet control and exercise. A number of drugs used to treat type 2 diabetes are GLP-1 agonists, including Wegovy, Ozempic (Semaglutide), Rybelsus, Saxenda, Trulicity(Dulaglutide) .Peptides Tirzepatide is the latest drugs to treat type 2 diabetes. What is GLP-1? Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone that promotes insulin secretion. It has the ability to reduce blood glucose levels in a glucose-dependent manner by enhancing insulin secretion. Natural GLP-1 is usually secrete in the gut after eating. It is susceptible to amidation and proteolytic cleavage and is broken down rapidly in the body, resulting in a known half-life of about 2 minutes. As a result, only 10% to 15% of GLP-1 enters the cycle in its entirety. To overcome this problem, They develop GLP-1 receptor agonists to increase GLP-1 activity. By activating GLP-1 receptor or prolonging the action time of GLP-1, GlP-1- based therapeutic drugs have the multi-effect mechanism of promoting β-cell generation and secretion of insulin, inhibiting α-cell secretion of glucagon, delaying gastric emptying and inhibiting appetite. To control blood sugar levels. At the same time, GLP is glucose-dependent and does not cause severe hypoglycemic symptoms. What is Tirzepatide wight loss? Tirzepatide basic information Cas No.:2023788-19-2 MF:C225H348N48O68 M , W: 4813.527 Bioavailability: 80% Route of administration: subcutaneous Elimination half-life: 5 days Tirzepatide, also known as LY3298176, or Mounjaro, is a linear polypeptide composed of 39 amino acids that has been chemically modified by lipylation to improve its uptake into cells and metabolic stability. In structure, Tirzepatide is an analogue of GIP. Fatty acids are attached to the base of GIP, thus having a longer half-life and higher affinity with albumin. Tirzepatide is a new type II diabetes drug. As an analog of GIP, Tirzepatide plays the similar role of GIP. At the same time, it is also a GLP-1 receptor agonist, which has the dual effects of lowering blood glucose and promoting gastrointestinal function, as well as promoting weight loss.

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https://www.astersteroids.com/the-neuronootropic-p , eptide-semax-benefits- dosage-and-use-in-bodybu , ilding/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Nootropic Semax, while developed based on the corticotropin 4-10 fragment (ACTH4-10), is a powerful neuro nootropic peptide drug. It was approved by the Government of the Russian Federation in 2011 as part of the list of important and essential medicines in Russia, mainly for the treatment of central nervous system diseases (including stroke, transient ischemic attack, optic nerve disease, etc.), memory and cognitive impairments, and the strengthening of the immune system. While Natural regulatory peptides are usually bioactive compounds produce by various cells. They provide connections between the major regulatory systems of the body, are direct regulatory substances or mediators of most physiological processes occurring in the body, and have a wide range of preventive and therapeutic effects. By modifying the natural regulatory peptide, it can have higher stability, so that it better apply in medical treatment. Nootropic Semax is a synthetic analogue of natural regulatory peptides. What is ACTH? Adrenocorticotropin (ACTH) and its fragments are one of the most active endogenous regulatory peptides. ACTH is a single chain polypeptide compose of 39 amino acids, which form in the anterior pituitary gland through the translation and processing of the precursor proteinogen melanocortin (POMC). ACTH is one of the major regulatory components of the pituitary-hypothalamic axis and interacts with the regulatory system of the hypothalamus. It can enhance the synthesis and secretion of glucocorticoid. In addition to its hormonal effects, ACTH also exhibits a wide range of extra-hormonal activities Multiple studies have shown that ACTH and its fragments can affect the behavior of human and animals. ACTH accelerates the learning process of animals, and it may directly act on the central nervous system without relying on the activity of ACTH hormone. A large number of studies have shown that the N-terminal region of ACTH is the main region responsible for the behavioral activity of hormones, while ACTH4-10 is the smallest fragment that retains the behavioral effect of ACTH molecule. ACTH and its fragments show neuroprotective and neurotrophic effects in addition to the role of puzzle. Studies have shown that even small doses of ACTH can stimulate the growth of nerve fibers. Peripheral nerve regeneration induced by ACTH and ACTH4-10 fragments was accompanied by significant enhancement of neuronal RNA and protein synthesis. ACTH also enhanced RNA and protein synthesis and glucose utilization in the brains of older animals. What is Nootropic Peptide Semax? Product name:Semax Other name:Met-Glu-His-Phe-Pro-Gly-Pro Cas:80714-61-0 , MF:C 37 H 51 N 9 O 10 S MW: 813.93 Purity :≥98% The Origin of Nootropic Semax The discovery of the remarkable intellectual, neuro protective, and neurotrophic effects of ACTH and its fragments makes this peptide one of the most promising candidates for the prevention and treatment of central nervous system diseases. However, these peptides are difficult to use in practice because of their extreme instability and short duration of action. The action time of ACTH4-10 is 30-60 min. After modification of different C- terminal, finding that the analogues carrying three C-terminal amino acids replace by Pro-Gly-Pro sequence show the longest activity. The peptide (h- met-glu-his-phi-pro-gly Pro-OH), is Semax, exhibits the intellectual- promoting effects of the natural prototype, while its action duration (Half- life) lasts 20-24 hours. The Application of Nootropic Peptide Semax In 2001, Nootropic Semax was developed to treat cerebral stroke. It has been shown to treat and prevent a wide range of diseases, including stroke, poor circulation encephalopathy, Parkinson’s disease, atrophy of the eyes, and a number of chronic conditions caused by insufficient blood circulation to the brain. Semax has shown high efficacy in preventive enhancement of intelligence in healthy people under extreme stress conditions. Nootropic Semax is also being developed to treat children with neurological defects (starting at age 3).

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https://www.astersteroids.com/neuropeptide-kisspep , tin-for-sale-with-good- quanity-activation-of-g , nrh-leads-to-release-of-fsh-and-lh/ Neurope , ptide Kisspeptin Cas:1848962-29-7 MF:C63H7 , 8N18O13 · xC2HF3O2 Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C What is Neuropeptide kisspeptin? Neuropeptide Kisspeptin, also known as kiss1, was first identified in 1996 as a transfer suppressor in human cell lines. The Kiss1 gene encodes a protein composed of 145 amino acids. In the human body, this protein is processed into a 54-amino acid peptide called kisspeptin, which, like several other neuropeptides, has a unique RF-amide motifs in its C-terminal region. It binds and activates the G-protein- coupled receptor GPR54, which stimulates hypothalamic neurons to release GnRH, leading to pituitary gonadotropin (LH and FSH) and sex hormone secretion. Kisspeptin is a key regulator of the onset of puberty, regulation of sex hormone-mediated gonadotropin secretion, and fertility control. Inactivated or activated mutations in Kiss1 and GPR54 genes are associated with hypogonadotropin hypogonadism (IHH) and precocious puberty (CPP). Neuropeptide kisspeptin has three main functions Activation of GnRH neurons in the hypothalamus leads to GnRH release, which leads to the release of FSH and LH. Inhibit the development of tumors. Treat low libido. How kisspeptin activates GnRH Neurons Bodybuilder is all too familiar with HPTA, the hypothalamic-pituitary- testicular axis whose positive and negative feedback controls the production and cessation of testosterone in men. HPGA is the hypothalamic-pituitary- gonadal axis. HPGA controls all stages of reproduction. The hypothalamus produces GnRH into the anterior pituitary and stimulates the secretion of LH and FSH. Slow GnRH pulsation is conducive to FSH secretion, while fast pulse frequency supports LH secretion. What is the hypothalamic-Pituitary-gonadal axis (HPGA)? The positive and negative feedback of the hypothalamic-pituitary-gonadal axis (HPGA) controls the secretion and cessation of sex hormones in both men and women, and its normal work maintains the normal levels of sex hormones in both men and women, thus maintaining physiological functions. This is something that happens every day in the adult body, and HPGA plays an important role in adult men and women. However, HPGA is not form in adulthood; all its components are establish in the foetus, activate in the neonatal period, then become stationary in childhood and cannot reactivate until puberty. GnRH Secretion Triggers Onset of Puberty Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are functional at birth, but after a perinatal hormone surge, they are directly suppressed in infancy and no longer function. Until puberty, dormant GnRH neurons are awakened to rerelease GnRH. GnRH secreted by the hypothalamus drives the pituitary gland to secrete the release of gonadotropin (follicle-stimulating hormone FSH and luteinizing hormone LH). In males, the increased release of GnRH pulses during puberty activates gonadotropin secretion, which in turn leads to increased testosterone secretion levels in the testis, binding with FSH to initiate spermatogenesis. Tetanic LH secretion consists of intermittent episodes of hormone secretion that reflect the corresponding pattern of pulsing GnRH release in the hypothalamus. In women, increased impulsive GnRH release also drives gonadotropin secretion, which is responsible for follicular formation and estradiol (E2) secretion. After puberty is complete, HPGA is officially complete and functional. Puberty begins through increase production of GnRH, however, it remains an open question how GnRH neurons activate during puberty.

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https://www.astersteroids.com/for-sale-best-qualit , y-anti-obesity-peptides- aod9604-with-good-pric , e-benefits-and-review/ Peptides AOD9604 Purity:99% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C When we know that AOD means Anti-Obesity Drug, we should know it is a diet drug when the word “AOD9604” comes into view. After we know it is diet pills, why we choose AOD9604 from all diet pills? Before we consider why we chose AOD9604, we need to know: What is AOD9604? What is AOD9604? First of all, AOD9604 s a Anti-Obesity drug, which is undisputed and completely true. Why develop a individual peptide AOD9604 from GH? Since 1959, Raben and Hollenberg first documented that GH has a significant lipolysis effect in adults, proving that GH can inhibit the differentiation of fat cells, reduce the accumulation of triglycerides, increase lipolysis, and thus reduce the quality of adipose tissue, GH has also been used by some people for the purpose of fat reduction. However, because GH also has a number of side effects, including glucose intolerance, insulin resistance, hypertension, and edema, these side effects have limited its development as a drug treatment for obesity. Studies of the structure and function of synthetic fragments of hormone molecules have shown that large proteins may contain many discrete functional domains, To control or influence a variety of specific physiological or biochemical actions. But identifying the functional domains of these fragments is not easy. After many years of research on GH, it was finally confirmed that the multifunctional GH molecule also contains different functional domains. It has been reported that the amino terminus of HGH molecule is the functional domain of the insulin-like action of HGH molecule, while the carboxyl terminus (C-terminus) of HGH molecule is the functional domain of the controlling substance. That’s where the new small molecule peptide AOD9604 comes in. What is AOD9604? AOD9604 also call as Tyr-hGH 177-191. Because it is actually a C-terminal fragment of human growth hormone (HGH), prepared by solid-phase peptide synthesis, it contains an additional tyrosine at its n-terminal for peptide stabilization and cyclization by a disulfide bond between two cysteine residues. The result was a new peptide, AOD9604. The C-terminal fragment of HGH (amino acids 177-191) is a structural region in HGH specifically responsible for lipids, which stimulates lipodecomposition and inhibits lipogenesis. HGH, as a human growth hormone, has synthetic metabolic properties, and its benefits are very clear to us, including increasing height, increasing muscle, burning fat and so on. However, it also has certain side effects, including glucose intolerance, diabetes and insulin resistance, acromegaly, cancer, edema and hypertension. For those who want to lose fat, nothing could be better than the fat- reducing properties of HGH while avoiding the possible side effects of HGH. Anti-Obesity AOD9604 was developed on this basis. AOD9604 vs HGH 176-191 AOD9604 is also known as Tyr-hGH 177-191, which is very similar to HGH 176- 191, and some people may confuse the two. HGH 176-191 is more like a transition between HGH and AOD9604. While HGH has reduced ester and many other benefits, AOD9604 focuses solely on fat loss and eliminates the side effects associated with HGH. HGH 176-191 is in the middle, which in addition to reducing fat, also stimulates IGF-1 secretion and increases blood IGF-1 levels. Therefore, HGH 176-191 will still affect the body’s glucose level and so on. So Anti-Obesity AOD9604 is a more targeted peptide with fewer side effects. If your goal is to lose weight, then, of these three, AOD9604 is the obvious choice.

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Product ID：TQPX005 Product Name：1,2,3-Triacetyl-5-deoxy-D-ribose CAS NO:62211-93-2 Molecular Formula：C11H16O7 Molecular Weight：260.24 Purity：≥98% Grade：Phar , maceutical Grade Appearance：White to off-white powder Application：Intermediate of Capecitabine Storage Conditions：Refrigerator

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Product ID：TQBO014 Product Name：Kinetin CAS NO:525-79-1 Molecular Formula：C10H9N5O Molecular Weight：215.21 Purity：≥99% Grade：Ultr , a Pure Grade Appearance：White crystal Application：For plant hormones, cytokinin, for biochemical reagents and biological hormones Storage Conditions：−20°C

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Product ID：TQNA012 Product Name：Cyclic AMP CAS NO:60-92-4 Molecular Formula：C10H12N5O6P Molecular Weight：329.21 Purity：≥98.5% Grade：Ph , armaceutical Grade Appearance：White Powder Application：The natural activator of cyclic adenosine - dependent protein kinase (PKA). CAMP is an important second messenger and is associated with neurotransmitters or hormone-induced receptor activation in many systems. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Storage Conditions：−20°C

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Product ID：TQNA015 Product Name：N2-Phenylacetyl guanosine CAS NO:132628-16-1 Molecular Formula：C18H19N5O6 Molecular Weight：401.38

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Product ID：TQBO026 Product Name：Streptomycin Sulfate CAS NO:3810-74-0 Molecular Formula：C42H84N14O36S3 Molecular Weight：1457.38 Purity： Grade：Ultra Pure Grade Appearance：White to off-white powder Application：For the treatment of tuberculosis, Clostridium and non-hemolytic streptococcal infective endocarditis, plague and rabid fever, influenza bacilli and Gram-negative bacilli Storage Conditions：2-8°C

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Product ID：TQBO012 Product Name：Insulin CAS NO:11070-73-8 Molecular Formula：C254H377N65O75S6 Molecular Weight：5733.49 Purity：≥ 94.0% Grade：Ultra Pure Grade Appearance：Light yellow powder and little smell of meet Application： Storage Conditions：2-8°C

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Product ID：TQAA002 Product Name：BOC-L-Leucine CAS NO:13139-15-6 Molecular Formula：C11H21NO4 Molecular Weight：231.29 Purity：≥99.0% Grade：Ph , armaceutical Grade Appearance：White to grayish white crystalline powder Application：Amino acid protective monomer and used for polypeptide synthesis Storage Conditions：−20°C

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