Pharmaceutical Intermediates

Product name:AC-262536 Chemical Name: 4-(3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)naphtha , lene-1- carbonitrile Synonyms: AC-262,536, AC-262536, CHEMBL468938, SCHEMBL4879629 CAS: 870888-46-3 Molar Mass: 278.348 g/mol Chemical Formula: C18H18N2O Storage: 2-8°C. Solubility: Ethanol. Packing:10g,100g,500g and 1kg AC-262536 is a compound which acts as a selective androgen receptor modulator. Chemically it possesses endo-exo isomerism, with the endo form being the active form. Activity of AC-262536: AC-262536 is a drug developed by Acadia Pharmaceuticals which acts as a selective androgen receptor modulator. Chemically it possesses endo-exo isomerism, with the endo form being the active form. It acts as apartial agonist for the androgen receptor with a Ki of 5nM, and no significant affinity for any other receptors tested. In animal studies it produced a maximal effect of around 66% of the anabolic action, but only around 27% of its potency as an androgen. More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: ACP-105 Synonyms: ACP105; ACP 105; ACE-XT; CAS: 899821-23-9 MF:C16H19ClN2O. MW:290.79 App , earance:White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Benefit: ▪ Increased growth of lean muscle mass and tissues ▪ Excellent for individuals with muscle-wasting conditions and osteoporosis ▪ Gain more muscles quickly and easily ▪ Increased strength ▪ Bone strength and density ▪ Increased on balance ▪ Speed ▪ Endurance ▪ Motor coordination ▪ Fat loss Application: ACP-105 is part of a class of molecules referred to as selective androgen receptor modulators (SARMs). SARMs may advance the standard of treatment for a variety of disorders including muscle-wasting conditions and osteoporosis, with fewer side effects as compared to current treatments based on test replacement. ACP-105 has exhibited promising pharmacological properties and a favorable safety profile in preclinical testing. More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: GW0742 CAS:317318-84-6 FW:C21H17F4NO3S2 MW:471.4846 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Benefit:The effects of a high-affinity PPAR-β/δ agonist, GW0742, in a mouse model of carrageenan (CAR)-induced pleurisy. Injection of CAR into the pleural cavity of mice elicited an acute inflammatory response characterized by accumulation of fluid containing a large number of neutrophils (polymorphonuclear leukocytes) in the pleural cavity, infiltration of polymorphonuclear leukocytes in lung tissues and subsequent lipid peroxidation, and increased production of nitrite/nitrate, TNF-α, and IL- 1β. Furthermore, CAR induced lung apoptosis (Bax and Bcl-2 expression), and nitrotyrosine formation was determined by immunohistochemical analysis of lung tissues. Administration of GW0742 (0.3 mg/kg, i.p. bolus) 30 min before and 30 min after a challenge with CAR caused a reduction in all the parameters of inflammation measured. Thus, based on these findings, we propose that a PPAR-β/δ agonist such as GW0742 may be useful in the treatment of various inflammatory diseases. Application:GW0742 is a potent and selective agonist for PPARδ, a member of the PPAR subfamily of the nuclear receptor superfamily of transcription factors. It has been shown to reduce atherosclerosis in LDLR-/- mice, to exert protective actions in an autoimmune model of demyelinating disease, and to induce differentiation and inhibit proliferation in keratinocytes. More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: S-23 CAS:1010396-29-8 MF:C18H13ClF4N2O3 M , W:416.753 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC How it works As a member of the SARM category, S23 works to selectively target and produce anabolic results in muscle and bone tissue without some of the limitations and side effects of traditional steroids. Benefits of S23 Many users and studies suggest that S23 is one of the most powerful SARMs on the market. We’ve listed the primary benefits you can expect when taking S23. S23 helps build lean muscle mass.The number one benefit of supplementing with S23 is its ability to increase lean body mass. The second core benefit is the proven ability to retain gains after completing a cycle, as shown in this study. S23 can increase strength and stamina during high-intensity workouts.Want to work out longer, harder and get better results every time you hit the gym? Users report enhanced speed, stamina, and endurance during workouts when supplementing with S23. Additionally, thanks to its ability to increase lean muscle tissue and decrease fat, high-intensity workouts and interval training can be optimized every time.One thing to note, however, is a user-reported side effect of increased anger whilst supplementing with S23, which may be a factor in increased effort and intensity during a workout. More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: SR9011 CAS No.: 1379686-30-2 Molecular formular: C20H24ClN3O4S Molecular Weight: 437.94 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Benefit：SR9011 suppressed the expression of BMAL1 messenger RNA in HepG2 cells in a REV-ERB-a/b-dependent manner. Moreover, SR9011 inhibited the activity of the SCNclock, with reversible inhibition of circadian oscillations. The C-terminal of sr9011 family proteins lacks a ligand binding domain, but the expression of Rev Erb protein can be inhibited by recruiting nuclear receptor inhibitors and histone deacetylase 3. Histone deacetylase 3 is a rev Erb agonist and a small molecular chemical probe. Fon Taine et al. First reported that sr9011 has a correlation with inflammation, sr9011 can inhibit the expression of TR4, thus controlling the inflammatory signal. Foreign scholars have found that in human macrophages, the increase of sr9011 mRNA expression by pharmacological methods directly leads to the decrease of pro- inflammatory factor IL-6 mRNA expression. Sr9011 increased the expression of chimeric Gal4 DNA binding domain in HEK293 cells in a dose-dependent manner to evaluate Rev Erb dependent inhibitory activity (DBD) - Rev Erb ligand binding domain (LBD) α or β and Gal4 responsive luciferase (Rev Erb α IC50 = 790 nm, Rev Erb β IC50 = 560 nm). More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: SR9009(Stenabolic ) CAS:1379686-30-2 MF:C20H24ClN3O4S MW:43 , 7.94026 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Benefit:Stenabolic (SR9009) possesses the capabilities of reducing obesity as well as reversing metabolic syndrome. In animal studies, it has shown to increase the metabolic activity of skeletal muscle in mice. Treated mice became lean while developing larger muscles. They also had a 50% increase in running ability, imitating the effect of aerobic exercise. Stenabolic alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. In simple terms, SR9009 sends a signal to the muscle to tell it to modify it's current metabolism. Application:SR9009,which is currently under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice.Treated mice become lean,develop larger muscles and can run much longer distances simply by taking SR9009,which mimics the effects of aerobic exercise.If similar effects can be obtained in people, the reversal of obesity,metabolic syndrome,and perhaps Type-II diabetes might be the very welcome result. Uses in bodybuilding More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: Ostarine (MK-2866) CAS: 1235370-13-4;1202044-20-9;841205-47-8 Molecular formula: C19H14F3N3O3 Molecular weight:389.328 Appearance: white powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Ostarine, also known as MK-2866, is in class of drugs called SARMS, which stands for selective androgen receptor modulators. Ostarine is selective in that it binds only to bone and muscle androgen receptors, which prevents things like prostate issues or hair loss or any of the other nasty side effects anabolic steroids can result in. This experimental drug was developed in 2009 by the company Gtx in an effort to fight muscle wasting diseases. As with many bodybuilding drugs, osta accidentally turned out to be a fantastic side effect free tool for fitness enthusiasts, bodybuilders and those with nagging injuries they've given up hope of healing. How Ostarine works? Ostarine binds to your muscles receptors and causes steroid-like muscle growth without side effects. These gains are absolutely "keepable" and maintainable after use is discontinued, as long as workouts stay consistent and diet remains on track. Ostarine helps nutrient partitioning to a high degree. This effect has helped many achieve the supposed "impossible" feat of losing fat while gaining muscle at the same time. More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Product Name: Ibutamoren mesylate,MK677,mk677,sarms CAS:159752-10-0 M , f:C27h36n4o5s.CH4o3s MW:624.776 Appearance:W , hite Powder Putity:99% Min. Package: 10g/bag or as customers'request. Test Method: HPLC The study found that a therapeutic benefit of MK677 as something called a “nonpeptide spiropiperidine” in eight healthy male adults. In these subjects, researchers found that MK677 promoted healthy nitrogen balance when combined with caloric reduction. The researchers found that this positive nitrogen balance was reported between days two and days seven of the study. Nitrogen balance in the body simply means that nitrogen intake is greater than nitrogen loss. There are three basic stages of nitrogen balance. Reason to Choose MK-677 1.MK-677 promoted healthy nitrogen balance when combined with caloric reduction. Nitrogen balance in the body simply means that nitrogen intake is greater than nitrogen loss. There are three basic stages of nitrogen balance. Positive nitrogen balance: this is the ideal state for muscle growth and it is a good indicator of the body and muscles’ ability to recover. Positive nitrogen intake with minimal nitrogen output means quicker recovery. A positive nitrogen balance is called an anabolic state. In an anabolic state, the body is not wasting away (catabolism). Negative nitrogen balance: this can be a dangerous state for frequently active people to be in, especially bodybuilders, weightlifters, or anyone trying to put on or maintain muscle. If positive nitrogen balance is anabolic, negative nitrogen balance is the complete opposite. Negative nitrogen balance contributes to muscle waste, fatigue, immune system weakness and diminished recovery capabilities. A body depleted of nitrogen inhibits your ability to naturally repair damaged cells. Equilibrium: as you probably guessed, this means that the body is consuming just as much nitrogen as it is excreting. From the study,we found that a therapeutic benefit of MK-677 as something called a “nonpeptide spiropiperidine” in eight healthy male adults. In these subjects, researchers found that MK-677 promoted healthy nitrogen balance when combined with caloric reduction. More detials,pls find me on www.astersteroid.com

Minimum Order: 10 long tons

Contact me Sharon Ye Mobile/Wechat/Skype/WhatsApp: +86 186 27159838 Email: sale2@whwingroup.com Website: http://www.whwingroup.com Product Name GW0742 Synonyms 2-(4-(((2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-m , ethylthiazol- 5-yl)methyl)thio)-2-methylphenoxy , );GW0742X;GW610742;GWdelta0742;2-(4-(((2-(3- Fl , uoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5- , yl)methyl)thio)-2- methylphenChemicalbooko;GW07 , 42;[4-[[[2-[3-FLUORO-4-(TRIFLUOROMETHYL)PHENYL]-4- , METHYL-5-THIAZOLYL]METHYL]THIO]-2-METHYLPHENOX , Y]ACETICACID;4-[2-(3-FLUORO-4- TRIFLUOROMETHYL- , PHENYL)-4-METHYL-THIAZOL-5-YLMETHYLSULFANYL]-2-MET , HYL-PHENOXY- ACETICACID CAS NO 317318-84-6 Molecular Formula C21H17F4NO3S2 Molecular Weight 471.49 Melting point  134.5-135.5 °C Boiling Point 591.5±60.0 °C(Predicted) Flash Point 311.5±32.9 °C Density  1.46±0.1 g/cm3(Predicted) Assay ≥98% (HPLC) Grade Pharmaceutical Grade Solubility Chloroform (Slightly), Methanol (Slightly) Appearance White Powder Storage store at dry and cool place Packing and Shipping Packing: Drum / Aluminum Foil Bag / According to customer's requiement Shipping: 3-5 working days after receive payment, by Fedex,UPS,EMS,DHL,Sea and air transport Usage It is the best in terms of endurance, energy, endurance and any type of performance improvement

Minimum Order: 1 bags

Contact me Sharon Ye Mobile/Wechat/Skype/WhatsApp: +86 186 27159838 Email: sale2@whwingroup.com Website: http://www.whwingroup.com Product Name SR9009 Synonyms SR9009sarms,whnohe_lucy(at)163.com;Ethyl3-[[[(4- chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]a , mino]methyl]-1- pyrrolidinecarboxylate;CS-2027; SR9009Powderwhnohe_Chemicalbookcarolineat163.c , om;Stenabolic(SR9009);SR9009;3- [[[(4-Chlorophe , nyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl , ]-1- pyrrolidinecarboxylicacidethylester; STENABOLIC CAS NO 1379686-30-2 Molecular Formula C20H24ClN3O4S Molecular Weight 437.94 Melting point 79-81°C Boiling Point 547.2±45.0 °C(Predicted) Flash Point 284.7±28.7°C Density 1.327±0.06 g/cm3(Predicted) Assay ≥99% Grade Pharmaceutical Grade Solubility DMSO (Slightly), Methanol (Slightly, Sonnicated) Appearance White Powder Storage store in tight,light resistance containers in a cool place Packing and Shipping Packing: Drum / Aluminum Foil Bag / According to customer's requiement Shipping: 3-5 working days after receive payment, by Fedex,UPS,EMS,DHL,Sea and air transport Usage It can increase weight loss, increase endurance, lower blood cholesterol, reduce inflammation, and reduce anxiety

Minimum Order: 1 bags

Contact me Sharon Ye Mobile/Wechat/Skype/WhatsApp: +86 186 27159838 Email: sale2@whwingroup.com Website: http://www.whwingroup.com Product Name 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrro , lidin-1- yl)-2-trifluoroMethyl)benzonitrile(LGD , -4033) Synonyms 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrro , lidin-1- yl)-2-trifluoroMethyl)benzonitrile(LGD , -4033);LGD-4033;4-[(2R)-2-[(1R)-2,2,2- Trifluor , o-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluorometh , yl)benzonitrile;4- ((R)-2-((R)-2,2,2-TriflChemi , calbookuoro-1-hydroxyethyl)pyrrolidin-1-yl)-2- , trifluoroMethyl)benzonitrile;LIGANDROL;4-[(2R)-2-[ , (1R)-2,2,2-trifluoro-1- hydroxyethyl]pyrrolidin , -1-yl]-2-(trifluoromethyl)benzonitrile; lgd4033sarmspowderlgd-4033ligandrol;POWDERLGD- , 4033LIGANDROL CAS NO 1165910-22-4 Molecular Formula C14H12F6N2O Molecular Weight 338.25 Melting point  N/A Boiling Point 439.9±45.0 °C(Predicted) Flash Point 219.8±28.7 °C Density  1.45±0.1 g/cm3(Predicted) Assay ≥98% Grade Pharmaceutical Grade Solubility Soluble in DMSO Appearance Solid Powder Storage Store at room temperature Packing and Shipping Packing: Drum / Aluminum Foil Bag / According to customer's requiement Shipping: 3-5 working days after receive payment, by Fedex,UPS,EMS,DHL,Sea and air transport Usage It is a powerful non-steroidal bodybuilding supplement used to increase muscle mass and reduce body fat

Minimum Order: 1 bags

Contact me Sharon Ye Mobile/Wechat/Skype/WhatsApp: +86 186 27159838 Email: sale2@whwingroup.com Website: http://www.whwingroup.com Product Name S-23 Synonyms Sarmspowder;S-23Sarms;S-23/S23,CASNO1010396-29- 8NewSarmsPowdermuslcebuilding;S23S23S-23;(S)-3-(4 , -chloro-3-fluorophenoxy)-N-(4- cyano-3-(trifluo , romethyl)phenyl)-2-hydroxy-2-methylpropanamide;S-2 , 3; (S)Chemicalbook-3-(4-Chloro-3-fluorophenoxy) , -N-(4-cyano-3- trifluoromethylphenyl)-2-hydroxy , -2-methylpropionamide;(2S)-3-(4-Chloro-3- fluor , ophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2- , hydroxy-2- methylpropanamide CAS NO 1010396-29-8 Molecular Formula C18H13ClF4N2O3 Molecular Weight 416.75 Melting point  119-121 °C Boiling Point 577.1±50.0 °C(Predicted) Flash Point N/A Density  1.48±0.1 g/cm3(Predicted) Assay ≥99% Grade Pharmaceutical Grade Solubility Ethanol Appearance White Powder Storage Store at room temperature, tightly sealed Packing and Shipping Packing: Drum / Aluminum Foil Bag / According to customer's requiement Shipping: 3-5 working days after receive payment, by Fedex,UPS,EMS,DHL,Sea and air transport Usage The main function is to increase muscle mass and reduce fat mass

Minimum Order: 1 bags

Contact me Sharon Ye Mobile/Wechat/Skype/WhatsApp: +86 186 27159838 Email: sale2@whwingroup.com Website: http://www.whwingroup.com Product Name Andarine Synonyms S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-( , 4-nitro-3- trifluoromethyl-phenyl)-propionamide , ;N-[4-Nitro-3-(trifluoromethyl)phenyl]- (2S)-3- , [4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropana , mideChemicalbook; Ostarine;S4PowderAndarineGTX-007SARMSteroidsCA , S401900-40-1forMuscleBuilding,mk- 2866,MK-2866; , CS-418;Andarine(S4)whnohe_caroline(at)163.com; Andarine(S4),whnohe_lucy(at)163.com;(1132656-7 , 3-5)ostarine CAS NO 401900-40-1 Molecular Formula C19H18F3N3O6 Molecular Weight 441.36 Melting point  70-74℃ Boiling Point 698.7±55.0 °C(Predicted) Flash Point N/A Density  1.47 Assay ≥99% Grade Pharmaceutical Grade Solubility "DMSO 88 mg/mL (199.38 mM) Ethanol 88 mg/mL (199.38 mM) Water Insoluble" Appearance White Powder Storage store at room temperature Packing and Shipping Packing: Drum / Aluminum Foil Bag / According to customer's requiement Shipping: 3-5 working days after receive payment, by Fedex,UPS,EMS,DHL,Sea and air transport Usage It is designed to treat osteoporosis without the development of the prostate and other secondary sex organs. Maintain lean body mass, speed up fat metabolism and increase lean body mass

Minimum Order: 1 bags

Contact me Sharon Ye Mobile/Wechat/Skype/WhatsApp: +86 186 27159838 Email: sale2@whwingroup.com Website: http://www.whwingroup.com Product Name ETHYL 2-PHENYLACETOACETATE Synonyms 2-Phenylacetoacetic acid ethyl ester;ETHYL 3-OXO-2- PHENYLBUTANOATE;ETHYL 2-PHENYLACETOACETATE;(2R)-3-oxo-2-phenylbutanoic acid ethyl ester;high quality 2-PHENYLACETOACETATE CAS 5413-05-8;Benzeneacetic acid, .alpha.-acetyl-, ethyl ester;2-Phenyl-3-oxobutanoic acid ethyl ester;2-Phenyl- 3-oxobutyric acid ethyl ester CAS NO 5413-05-8 Molecular Formula C12H14O3 Molecular Weight 206.24 Melting Point 140-144°C/10mm Boiling Point 140-144°C 10mm Flash Point 140-144°C/10mm Density 1,085 g/cm3 Assay 99% Grade Phamaceutical Grade Solubility Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water. Appearance White crystalline powder Storage Keep containers tightly closed in a dry, cool and well-ventilated place Packaging and Shipping Aluminum foil bag, cartons, plastic contain,drums or as required; By Express, by Air, by Sea according to the Amount Usage Mainly use in Pharmaceutical Intermediates/medical intermediate/ research purpose

Minimum Order: 1 bags