Chemicals & Plastics

https://www.astersteroids.com/the-neuronootropic-p , eptide-semax-benefits- dosage-and-use-in-bodybu , ilding/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Nootropic Semax, while developed based on the corticotropin 4-10 fragment (ACTH4-10), is a powerful neuro nootropic peptide drug. It was approved by the Government of the Russian Federation in 2011 as part of the list of important and essential medicines in Russia, mainly for the treatment of central nervous system diseases (including stroke, transient ischemic attack, optic nerve disease, etc.), memory and cognitive impairments, and the strengthening of the immune system. While Natural regulatory peptides are usually bioactive compounds produce by various cells. They provide connections between the major regulatory systems of the body, are direct regulatory substances or mediators of most physiological processes occurring in the body, and have a wide range of preventive and therapeutic effects. By modifying the natural regulatory peptide, it can have higher stability, so that it better apply in medical treatment. Nootropic Semax is a synthetic analogue of natural regulatory peptides. What is ACTH? Adrenocorticotropin (ACTH) and its fragments are one of the most active endogenous regulatory peptides. ACTH is a single chain polypeptide compose of 39 amino acids, which form in the anterior pituitary gland through the translation and processing of the precursor proteinogen melanocortin (POMC). ACTH is one of the major regulatory components of the pituitary-hypothalamic axis and interacts with the regulatory system of the hypothalamus. It can enhance the synthesis and secretion of glucocorticoid. In addition to its hormonal effects, ACTH also exhibits a wide range of extra-hormonal activities Multiple studies have shown that ACTH and its fragments can affect the behavior of human and animals. ACTH accelerates the learning process of animals, and it may directly act on the central nervous system without relying on the activity of ACTH hormone. A large number of studies have shown that the N-terminal region of ACTH is the main region responsible for the behavioral activity of hormones, while ACTH4-10 is the smallest fragment that retains the behavioral effect of ACTH molecule. ACTH and its fragments show neuroprotective and neurotrophic effects in addition to the role of puzzle. Studies have shown that even small doses of ACTH can stimulate the growth of nerve fibers. Peripheral nerve regeneration induced by ACTH and ACTH4-10 fragments was accompanied by significant enhancement of neuronal RNA and protein synthesis. ACTH also enhanced RNA and protein synthesis and glucose utilization in the brains of older animals. What is Nootropic Peptide Semax? Product name:Semax Other name:Met-Glu-His-Phe-Pro-Gly-Pro Cas:80714-61-0 , MF:C 37 H 51 N 9 O 10 S MW: 813.93 Purity :≥98% The Origin of Nootropic Semax The discovery of the remarkable intellectual, neuro protective, and neurotrophic effects of ACTH and its fragments makes this peptide one of the most promising candidates for the prevention and treatment of central nervous system diseases. However, these peptides are difficult to use in practice because of their extreme instability and short duration of action. The action time of ACTH4-10 is 30-60 min. After modification of different C- terminal, finding that the analogues carrying three C-terminal amino acids replace by Pro-Gly-Pro sequence show the longest activity. The peptide (h- met-glu-his-phi-pro-gly Pro-OH), is Semax, exhibits the intellectual- promoting effects of the natural prototype, while its action duration (Half- life) lasts 20-24 hours.

Minimum Order: 10 long tons

https://www.astersteroids.com/tirzepatide-a-new-du , al-action-type-ii- diabetes-drug-showed-better- , weight-loss-results-than-semaglultide/ Purity:9 , 8% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Tirzepatide is a drug approved for medical use in the United States, European Union, Canada and Australia for the treatment and control of type 2 diabetes mellitus. As a dual GIP and GLP-1 receptor agonist, it is the first of its kind. What is Tirzepatide for Type 2 Diabetes? The incidence of type 2 diabetes has been on the rise worldwide in recent years, with about 420 million adults worldwide, 30 million people in the United States and 114 million people in China having type 2 diabetes. Globally, one person dies every six seconds from complications related to type 2 diabetes. Type 2 diabetes is the eighth leading cause of death in the world. Obesity and overweight are important risk factors for type 2 diabetes, and about 80-90% of type 2 diabetes patients are overweight or obese. Type 2 diabetes mellitus, also known as non-insulin-dependent diabetes mellitus, is a chronic metabolic disease characterize by pancreatic beta cell dysfunction and insulin resistance. Treatment for this disease focuses on controlling blood sugar, improving insulin resistance and protecting pancreatic beta cell function. The main methods are insulin therapy, oral hypoglycemic drugs, diet control and exercise. A number of drugs used to treat type 2 diabetes are GLP-1 agonists, including Wegovy, Ozempic (Semaglutide), Rybelsus, Saxenda, Trulicity(Dulaglutide) .Peptides Tirzepatide is the latest drugs to treat type 2 diabetes. What is GLP-1? Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone that promotes insulin secretion. It has the ability to reduce blood glucose levels in a glucose-dependent manner by enhancing insulin secretion. Natural GLP-1 is usually secrete in the gut after eating. It is susceptible to amidation and proteolytic cleavage and is broken down rapidly in the body, resulting in a known half-life of about 2 minutes. As a result, only 10% to 15% of GLP-1 enters the cycle in its entirety. To overcome this problem, They develop GLP-1 receptor agonists to increase GLP-1 activity. By activating GLP-1 receptor or prolonging the action time of GLP-1, GlP-1- based therapeutic drugs have the multi-effect mechanism of promoting β-cell generation and secretion of insulin, inhibiting α-cell secretion of glucagon, delaying gastric emptying and inhibiting appetite. To control blood sugar levels. At the same time, GLP is glucose-dependent and does not cause severe hypoglycemic symptoms. What is Tirzepatide wight loss? Tirzepatide basic information Cas No.:2023788-19-2 MF:C225H348N48O68 M , W: 4813.527 Bioavailability: 80% Route of administration: subcutaneous Elimination half-life: 5 days Tirzepatide, also known as LY3298176, or Mounjaro, is a linear polypeptide composed of 39 amino acids that has been chemically modified by lipylation to improve its uptake into cells and metabolic stability. In structure, Tirzepatide is an analogue of GIP. Fatty acids are attached to the base of GIP, thus having a longer half-life and higher affinity with albumin. Tirzepatide is a new type II diabetes drug. As an analog of GIP, Tirzepatide plays the similar role of GIP. At the same time, it is also a GLP-1 receptor agonist, which has the dual effects of lowering blood glucose and promoting gastrointestinal function, as well as promoting weight loss.

Minimum Order: 10 long tons

https://www.astersteroids.com/type-2-diabetes-trea , tment-semaglutide- wegovy- fda-approved-for- , heal , thy-weight-loss/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Peptides Semaglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist. Currently, we know that there are three products approved by the US FDA that contain semaglutide: Ozempic, Rybelsus and Wegovy. Among them, Ozempic and Rybelsus are mainly use for type 2 diabetes, and Wegovy(Semaglutide) use for weight loss. Details as below: What is GLP-1? GLP-1, or glucagon-like peptide-1, is a hormone that naturally producing in the body. It mainly produce in the gut. GLP-1 plays a crucial role in regulating blood sugar levels and appetite. In consuming food, GLP-1releasing into the blood, and it has several effects on the body. Stimulates insulin release: GLP-1 enhances insulin release. Insulin lowers blood sugar levels by encouraging glucose to enter cells. Inhibition of glucagon release: GLP-1 inhibits the release of glucagon, another hormone produced by the pancreas. Glucagon raises blood sugar levels by promoting the release of stored glucose in the liver. Slow gastric emptying: GLP-1 slows the rate at which the stomach dumps its contents into the intestines. This delay in gastric emptying helps reduce the rapid rise in blood sugar levels after a meal. Appetite suppression: GLP-1 acts on the brain to suppress appetite and promote satiety. Given these roles, GLP-1 plays a crucial role in regulating glucose metabolism in the body and promoting glucose control. Development of GLP-1 receptor agonists that can mimic the effects of GLP-1 to improve blood sugar control and weight loss in patients with type 2 diabetes or obesity. That’s what Semaglutide is like. How Semaglutide works? Peptides Semaglutide, first use to treat type 2 diabetes and obesity, acts as a GLP-1 receptor agonist by mimicking GLP-1 action. When inject Semaglutide, it binds to and activates GLP-1 receptors locating on various cells in the body, including pancreatic cells. By stimulating the release of insulin, glucose in the blood encourage to enter cells, thereby lowering blood sugar levels. Sugars that enter the cell also provide energy to the cell; By inhibiting glucagon, the liver does not produce excess glucose, thereby reducing blood sugar levels. By slowing stomach emptying, it reduces the rate at which nutrients, including glucose, are absorbed into the bloodstream, helping to control blood sugar spikes after meals. This effect prevents people from feeling hungry as soon as possible and does not produce the desire to eat, which helps people with type 2 diabetes or obesity control their appetite. Semaglutide also affects appetite regulation centers by acting on the brain, resulting in reduced hunger and increased feelings of gulping. Helps to control appetite and lose weight. Overall, Semaglutide helps improve blood sugar control in people with type 2 diabetes by increasing insulin release, inhibiting glucagon secretion, and slowing digestion, while having the effect of reducing weight control.

Minimum Order: 10 long tons

Product link to :https://www.astersteroids.com/new-sarms-powder-ac , -262536- ac262-price-dosage-benefits-for-bo , dybu , ilding-cas870888-46-3/ AC-262 536 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product name:AC-262536 Chemical Name: 4-(3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)naphtha , lene-1- carbonitrile Synonyms: AC-262,536, AC-262536, CHEMBL468938, SCHEMBL4879629 CAS: 870888-46-3 Molar Mass: 278.348 g/mol Chemical Formula: C18H18N2O Storage: 2-8°C. Solubility: Ethanol. Packing:10g,100g,500g and 1kg AC-262536 is a compound which acts as a selective androgen receptor modulator. Chemically it possesses endo-exo isomerism, with the endo form being the active form. Activity of AC-262536: AC-262536 is a drug developed by Acadia Pharmaceuticals which acts as a selective androgen receptor modulator. Chemically it possesses endo-exo isomerism, with the endo form being the active form. It acts as apartial agonist for the androgen receptor with a Ki of 5nM, and no significant affinity for any other receptors tested. In animal studies it produced a maximal effect of around 66% of the anabolic action, but only around 27% of its potency as an androgen.

Minimum Order: 10 long tons

Aicar powder Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Brief Description: AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P. Product link to :https://www.astersteroids.com/aicar-acadesine-bod , ybuilding- price-good-quality-for-sale-bene , fits , -effect-and-dosage-cas2627-69-2/ Product Name: AICAR/ Acadesine Synonyms:AICA Riboside; Acadesine CAS:2627-69-2 MF:C9H14N4O5 MW:258.23 Appearance:White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Benefit: ▪ Its effect in increasing the uptake of glucose in the body. Glucose is the source of energy and the increased uptake means that your body is spending more energy than before. While this will be a great thing for working out, it can also help improve energy levels, keeping you active all day. ▪ To improve metabolic action significantly. Even for people who just want to use the drug as a simple weight loss solution without difficult workout regimens, it can help set the metabolism right so that you can burn more even at rest. ▪ Aicar is also a selective supplement that targets only the skeletal cells and the muscle tissue. This can help people who are extremely obese fine tune their body to a place where they can start an exercise routine. Aicar has also often been referred to as “exercise in a bottle”. In other words, it’s a solution that can help you lose weight by doing nothing.

Minimum Order: 10 long tons

Product link to :https://www.astersteroids.com/new-sarms-powder-ac , p-105- benefit-dosage-for-bodybuilder-loss-fat- , cas899821-23-9/ Product Name: ACP-105 Synonyms: ACP105; ACP 105; ACE-XT; CAS: 899821-23-9 MF:C16H19ClN2O MW:290.79 Appe , arance:White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC Benefit: ▪ Increased growth of lean muscle mass and tissues ▪ Excellent for individuals with muscle-wasting conditions and osteoporosis ▪ Gain more muscles quickly and easily ▪ Increased strength ▪ Bone strength and density ▪ Increased on balance ▪ Speed ▪ Endurance ▪ Motor coordination ▪ Fat loss Application: ACP-105 is part of a class of molecules referred to as selective androgen receptor modulators (SARMs). SARMs may advance the standard of treatment for a variety of disorders including muscle-wasting conditions and osteoporosis, with fewer side effects as compared to current treatments based on test replacement. ACP-105 has exhibited promising pharmacological properties and a favorable safety profile in preclinical testing. How Strong Is ACP-105? To get a clear representation of just how strong of an effect this SARM has, each research subject undergoes ORX-induced atrophy (an orchiectomy), which is a surgical procedure in which one or both testicles are removed. This is the surgical form of castration. The point of this is that once the ACP-105 is administered to the research subjects, you can calculate an exact figure that defines how anabolic and androgenic a compound is, based on the fact that there are no longer endogenous hormones skewing the results, and the research subject is essentially functioning from a baseline reading of 0 on all accounts. 1mg/kg per day was given to the research subjects, and that resulted in a very blatant anabolic effect. The extent of this anabolic effect is measured in what % of hypertrophy occurs relative to the baseline that DHT would otherwise achieve had the research subject not undergone ORX-induced atrophy. The % of anabolic activity was determined to be 67%, with only 21% reversal of the prostate gland (which is used to measure androgenic activity). From this we can conclude that this SARM has an anabolic:androgenic rating/ratio of 3.19:1 There are several SARMs that have anabolic:androgenic ratios of 3:1 and up though, so this is fairly typical. While we can vaguely gather what we can expect from this compound (the comparisons that come to mind are Ostarine and S4), without knowing the binding affinity of the compound we can essentially only make shot in the dark guesses. We do know what kind of interaction ACP-105 has with the androgen receptor though, which helps shed light on things a bit more. Based on the information that was available, we know that ACP-105 is a partial agonist. Full agonists induce greater levels of suppression, but are more potent (based on the information presented). Partial agonists on the other hand, are less suppressive, but are typically weaker relative to Testosterone and DHT, which is the case with ACP-105.

Product link to:https://www.astersteroids.com/safe-shipping-sar , ms-gw0742- powder-with-99-purity-cas317318-84-6 , -benefits-for-bodybuilding/ Sarms GW0742 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: GW0742 CAS:317318-84-6 MF:C21H17F4NO3S2 M , W:471.4846 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC When you see below two 2D molecular structure,you must have concerns: What are they? What’s the relationship between them? When we firstly the 2D molecular structure of them,we should think they are the same. If we identify them carefully, we can find the difference between 2D molecular structures is the one F atom. The 2D molecular structure in left without F atom belongs to GW501516,with MF:C21H18F3NO3S2. The 2D molecular structure in right with a F atom belongs to GW0742,with MF: C21H17F4NO3S2. Based on the 2D molecular structure above, we could thought that GW0742 and GW501516 have similar effects. In fact, GW0742 and GW501516 are also PPAR agonists. So, one f-Atom difference,makes what appearances to these two products? First of all, GW501516 is a relatively mature product. It has been more than 30 years since its initial discovery, while GW0742 is a new product that is still in the research stage. Replacing an H Atom with an F Atom makes GW0742 a new product and a new patent that extends the GW501516 patent, bringing about corresponding economic benefits and providing a new choice for the corresponding users. Second, replacing an H atom with an F atom improves the bioavailability and potency of the drug. A few years ago, chemists discovered that strategically replacing weaker C-H bonds with stronger C-F bonds alleviates or eliminates structural weaknesses in drug molecules, significantly improving their metabolic stability. Although H atom and F Atom are obviously different in some respects, they are comparable in size, so substituting F Atom for H Atom can generally be considered to have little effect on bond (drug) structure. More importantly, due to the different electronic properties of H and F, strategic placement of F Atom can establish additional interactions with its target, thereby increasing the desired activity. Moreover, substituting F into a drug molecule could alter its properties, increasing its bioavailability and making it more easily absorbed by the body. Meanwhile, we know that the length of the CH chain affects the half-life of the molecule. GW0742 replaces the C-H bond with the C-F bond, which has many corresponding advantages. However, as the C-H bond is replaced, the length of the CH chain of GW0742 becomes shorter, which makes the half-life of GW0742 shorter than that of GW501516. GW0742 works in much the same way as GW501516, but the C-H bond is replaced by the C-F bond, making GW0742 more effective than GW501516 in some areas. Such as: GW0742 reverses the flow of cholesterol into the bloodstream, effectively lowering cholesterol levels in the body. GW0742 improves the body’s lipid metabolism in very small doses, allowing it to better process the body’s lipids. GW0742 can help reduce inflammation in the gut by reducing swelling, resulting in significant relief for patients. GW0742 has the same effect as GW501516 in activating AMP activated protein kinase, glucose uptake and fatty acid oxidation in skeletal muscle. Therefore, GW0742 has a higher bioavailability and potency, a shorter half- life and a higher price. GW501516 is more mature, has a longer half-life and is more convenient to use. We can choose to buy GW0742 or GW501516 according to our concern.

Minimum Order: 10 long tons

Sarms S-23 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country S-23 is an modern selective androgen receptor modulator (SARM) with the added interest in its potential for male hormonal contraceptive. It binds to the androgen receptor more strongly than older compounds such as Andarine with a Ki of 1.7nM, and in animal studies it showed both a good ratio of anabolic to androgenic effects, and dose-dependent suppression of spermatogenesis with spontaneous recovery after cessation of research. Brief Description:S-23 is an modern selective androgen receptor modulator (SARM) with the added interest in its potential for male hormonal contraceptive. Product link to :https://www.astersteroids.com/high-quality-sarm-s , 23- powder- 99-purity-benefits-effect-and-do , sage , -for-bodybuilding-cas1010396-29-8/ Product Name: S-23 CAS:1010396-29-8 MF:C18H13ClF4N2O3 M , W:416.753 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC How it works As a member of the SARM category, S23 works to selectively target and produce anabolic results in muscle and bone tissue without some of the limitations and side effects of traditional steroids. Benefits of S23 Many users and studies suggest that S23 is one of the most powerful SARMs on the market. We’ve listed the primary benefits you can expect when taking S23. S23 helps build lean muscle mass.The number one benefit of supplementing with S23 is its ability to increase lean body mass. The second core benefit is the proven ability to retain gains after completing a cycle, as shown in this study. S23 can increase strength and stamina during high-intensity workouts.Want to work out longer, harder and get better results every time you hit the gym? Users report enhanced speed, stamina, and endurance during workouts when supplementing with S23. Additionally, thanks to its ability to increase lean muscle tissue and decrease fat, high-intensity workouts and interval training can be optimized every time.One thing to note, however, is a user-reported side effect of increased anger whilst supplementing with S23, which may be a factor in increased effort and intensity during a workout. S23 can increase fat loss .S23 is to increase fat loss and fat oxidization.The study showed that rats treated with S23 increased lean muscle mass and bone mineral density whilst simultaneously reducing fat loss percentage. Interestingly, this study shows that there is an inverse relationship between a higher dose of S23 and a decrease in body fat. This suggests that a higher dose of S23 results increased fat loss.

Minimum Order: 10 long tons

Product link to :https://www.astersteroids.com/safe-shipping-99-pu , rity- sarm- yk11-steroid-for-bodybuilding-do , sage , -effect-and-benefit-cas431579-34-9/ Sar , ms yk11 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: YK11 CAS:431579-34-9 MF:C152h252n44o42 MW , :3367.2 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC YK11 Benefits: YK-11 induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8) as a myokine, a protein produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. In addition to that, YK-11 is a bit leaner than LGD-4033, and is excellent for lean gains on par with testosterone. It produces lean, dry, easily kept gains in strength and muscle, and reductions in bodyfat. YK-11 selectively binds to the androgen receptors similarly to LGD-4033, and MK-2866. That is to say, that YK-11 offers great promise as therapy for muscle wasting illnesses, and for promoting very massive muscle gains. Much like MK-2866, and LGD-4033, YK-11 binds to the androgen receptors in muscle, and bone. YK-11 is weakly anabolic to androgenic ratio of greater than 25:1. This means that YK-11 is very weakly androgenic, and provides anabolic effects while minimizing the negative effects on the prostate and other organs. YK-11 appears to be weakly suppressive to the Hypothalamic Pituitary Testicular Axis (HPTA), but far less so than any anabolic steroids or prohormones. YK-11 users have observed no elevations in estrogen, and decreases sex hormone binding globulin (which would result in a raised free testosterone, but not total testosterone). In addition to that, YK-11 is a bit leaner than LGD-4033, and is excellent for lean gains on par with testosterone. It produces lean, dry, easily kept gains in strength and muscle, and reductions in bodyfat.

Minimum Order: 10 long tons

Product link to:https://www.astersteroids.com/high-quality-sarm , s-powder- lgd- 3303-with-99-purity-cas116591 , 0-22 , -4/ Sarms LGD-3303 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: LGD-3303 CAS:1165910-22-4 MF:C16H14ClF3N2O MW:342.7433696 Appearance: Light Yellow powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC In order to determine plasma concentrations, the LGD-3303 standard solution was added to blank rat plasma; calibration standards were constructed from 0.001 to 10 μg/ml; 250 μl acetonitrile containing LGD-2226 was used as an internal standard (Miner et al., 2007). 50 μl of the calibration standard and 50 μl of the plasma sample were extracted by protein precipitation. After centrifugation, the supernatant was analyzed by liquid chromatography (LC) for LGD-3303 followed by tandem mass spectrometry. To determine the tissue concentration, the standard solution of LGD-3303 was added to blank rat tissues in a 2:1 ratio (v/w) standard solution and tissue. A calibration standard (from 0.01-5 μg/ml) was constructed in an extraction solution [Acetonitrile/water = 70:30 (v/v)] containing LGD-2226 as an internal standard. The tissue sample was extracted with 2 volumes of an extraction solution containing an internal standard. After overnight extraction, the supernatant was analyzed for LGD-3303 by LC tandem mass spectrometry. The analysis was performed by electrospray ionization mass spectrometry (MS) using an Applied Biosystems API 4000 or API 4000/Q-trap (Applied Biosystems, Foster City, CA). Samples were analyzed by injecting 10 to 20 μl of the supernatant into the LC/MS instrument. The LC instrument was equipped with a C8 octyl, MOS guard column (4 x 2 mm; Phenomenex, Torrance, CA) and a Gemini C6-phenyl column (50 x 2.0 mm, 5 [mu]m; Phenomenex). The mobile phases A and B are respectively 0.1% formic acid in H2O and 0.1% formic acid in acetonitrile. A multi-reaction monitoring scan using 343.1 / 245.3 atomic mass units was monitored in positive mode. Benefit:LGD-3303 has been developed to help address a wide range of conditions. However, the most important is its ability to maintain the beneficial effects of androgens in improving muscle mass and bone density without the side effects. Although the selective mechanism of LGD-3303 and other SARMs is not yet clearly understood even with ongoing research, it is clearly a big leap from the usual supplyment. Application:LGD-3303 is a selective androgen receptor modulator (SARM) that comes with impeccable oral bioavailability. It is categorized as a selective agonist designed for the androgen receptor. LGD-3303 has androgenic effects and at the moment it is being researched as a possible solution to treat osteoporosis.

Minimum Order: 10 long tons

product link to :https://www.astersteroids.com/one-of-the-most-pow , erful- sams-sr9009-for-females/ Sarms SR9009 CAS:1379686-30-2Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: SR9009(Stenabolic ) CAS:1379686-30-2 MF:C20H24ClN3O4S MW:43 , 7.94026 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers'request. Test Method: HPLC SR9009 (also known as Stenabolic) is commonly classified as SARMs because it has similar effects to SARMs, although it is clear that SR9009 is fundamentally a Rev-ERB agonist. So the question is, is SR9009 suitable for female? The answer is: suitable. SR9009 is a metabolic regulator that increases endurance by regulating body metabolism. It doesn’t produce androgens like steroids, so it doesn’t masculinize female! There are plenty of extra surprises for female to use with the SR9009. SR9009 stimulates the body’s metabolic function, increases skeletal muscle activity, and increases endurance while burning calories. For some frail female, increasing stamina can get you to your desired goals faster. The human skeletal muscle stores water content, protein, and minerals. While SR9009 improves the quality of skeletal muscle, it also increases the storage capacity of skeletal muscle. Skeletal muscle is like a warehouse. SR9009 can expand the warehouse and improve the strength of the warehouse. The improvement of skeletal muscle water content can make women’s skin more lustrous, and the improvement of protein and minerals can make their body healthier, thus preventing various inflammations, and adequate exercise can make your sleep more fulfilling! SR9009 dosage for females Due to the different body structure of female and male, the dosage of SR9009 for female and male is also slightly different. SR9009 dosage for females: The recommended cycle of SR9009 for females is 8- 10 weeks, and the recommended dosage is 5-20mg per day. Due to the short half-life of SR9009, which is only about 4 hours, it is used about three times a day, and it is recommended to take it after three meals. SR9009 male dosage: The recommended cycle for men to use SR9009 is 8-12 weeks, and the recommended dosage is 10-30mg per day. Please note that for your own health, please do not overdose.

Minimum Order: 10 long tons

Product link to:https://www.astersteroids.com/safe-shipping-sar , ms-sr9011- powder-for-bodybuilding-cycle-for-sa , le-cas1379686-30-2/ Sarms SR9011 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: SR9011 CAS No.: 1379686-30-2 Molecular formular: C20H24ClN3O4S Molecular Weight: 437.94 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC SR9011 and SR9009, both of them are Rev-ERB agonists, were originally used to study circadian rhythm regulation, immune system function, inflammation and cancer. A paper published in Nature in 2018, which activated Rev-ERB with SR9011 or SR9009, surprised the world with a breakthrough in the treatment of cancer. At the time, it was claimed that targeting Rev-ERB could starve cancer cells without affecting normal ones. With the deepening of research, and because Rev-ERB is mainly located in muscle tissue, bone, liver and adipose tissue, people gradually find that SR9011/SR9009 also plays a great role in fitness. Gradually SR9011 and SR9009 was developed for fitness, after all, the fitness population is much larger than the cancer population. SR9011 and SR9009 play basically the same role when they are used for fitness. The only difference can be seen from their molecular formula. The molecular formula of SR9009 is C20H24ClN3O4S The molecular formula of SR9011 is C23H31ClN4O3S We can see that SR9011 has more C3H7N1 than SR9009, and of course, an O is missing. From the molecular structure of them,we can know that SR9011 has three more hydrocarbon chains than SR9009, and -NH-(amine group) replaces -O-(carbonyl group). This makes SR9011 more bioavailable and has a longer half-life than SR9009. SR9009, as a more mature compound than SR9011, has been widely confirmed in the field of fitness. The effect of SR9009 is very good, but its bioavailability is not particularly high. Therefore, more people choose subcutaneous injection rather than oral injection, which can produce better effects. The -NH- (amine group) in SR9011 improves its bioavailability, making it more effective, and can be used in a variety of ways, such as oral, gel, injection, etc. The length of the hydrocarbon chain directly affects the half-life of the compound. The short half-life of SR9009, which is about 4 hours, makes it necessary to give SR9009 frequently, with a daily dose spread out over 3-4 times. SR9011 has a longer hydrocarbon chain, allowing a single use of SR9011 to take effect for about twice as long as SR9009. The longer half-life allows us to inject less frequently. This makes the SR9011 a good alternative.

Minimum Order: 10 long tons

Product link to:https://www.astersteroids.com/for-sale-andarine , -s4-sarms- powder-for-bodybuilding-cycle-fat-lo , ss-cas401900-40-1/ Sarms Andarine Other Name:S4 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: Andarine(S4) CAS: 401900-40-1 Molecular Formular: C19H18F3N3O6 Molecular Weight: 441.36 Appearance: Pale yellow powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC Compared with the whole SARMs group, S4 has two obvious functions, which make it have a special position in SARMs. First, S4 not only increases muscle but also reorganizes muscle tissue and modifies muscle shape. The second is to enhance the distribution of blood vessels. In addition to the pursuit of health, the purpose of Bodybuilding is to increase muscle mass. All products in SARMs have the effect of increasing muscle mass. However, after increasing muscle mass, whether the muscle shape is appropriate is a new issue to be considered. At this point, the S4 becomes particularly important. The S4, the first SARMs developed in the 1990s, was developed to treat various muscular dystrophy diseases as a major reason for its development and subsequently proved to be incredibly effective in improving muscular dystrophy. Targeting androgen receptors in muscle and bone tissue, S4 promotes muscle growth while improving muscle density and firmness, giving muscles a clearer and torn appearance. This effect is achieved through a series of anabolic reactions of S4. Basically, the reaction works by limiting glucose absorption into cells and promoting protein synthesis without recourse to insulin or any growth hormone. In addition to boosting protein synthesis, it also blocks the effects of myostatin. Myostatin is an autocrine and paracrine hormone that prevents muscle formation, so it is crucial that S4 controls the effects of myostatin. During this reaction, S4 attaches to proteins and binds to them to control muscle growth and remodeling, resulting in drier, clearer modified muscles. From the above, we know the important role of S4 in muscle building, but we should not ignore the muscle-building effect of S4. After completing an S4 cycle, we can increase lean muscle by more than 8kg. Therefore, the S4 is probably the most suitable cutting product in SARMs. It is also a key turning point from fitness to bodybuilding. An additional specific effect of S4 is increased vascular distribution, which targets the destruction of accumulated triglycerides and increases the number of blood vessels in adipose tissue, resulting in significant weight loss and improved muscle sharpness. Human body every 6.5 square centimeter of skin with blood vessels around 6.1 meters long, good blood vessels to let a person look very comfortable, energetic, artery blood vessel diameter, wall smooth, soft, good elasticity, strong ability to pump blood, but some blood vessels not worrying, just like the water pipe in the home, use a long time, The inner wall of the pipeline will scale, rust, and gradually lead to blocked pipes and unable to supply water. In blood “scale” it is to point to cholesterol, triglyceride ester to wait, they accumulate more and more on blood vessel wall, form the plaque of atherosclerosis of as yellow millet. As time passes, the elasticity of blood vessel wall drops, blood flow is blocked, and eventually heart and cerebrovascular diseases are caused by ischemia. For bodybuilder, a good vascular level helps to have a smooth bodybuilding. S4 also increases the distribution of blood vessels, making them more prominent and further modifying the shape of muscles. After all, the S4 is ideal for dynamic cutting cycles, fat loss and muscle rebuilding without the need of supplements and stacks in principle.

Minimum Order: 10 long tons

Product link to:https://www.astersteroids.com/safe-shipping-mk- , 2866- mk2866- ostarine-sarms-powder-buy-for- , body , building-dosage-and-cycle/ Sarms MK-2866 Other Name:Ostarine Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: Ostarine (MK-2866) CAS: 1235370-13-4;1202044-20-9;841205-47-8 Molecular formula: C19H14F3N3O3 Molecular weight:389.328 Appearance: white powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC Ostarine/MK 2866 Cycle For bodybuilding Ostarine( MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients Ostarine/MK 2866 Cycle For cutting Nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder. Ostarine/MK 2866 Cycle For Recomping Ostarine shines in recomping due to its nutrient portioning results. Calorie is used to build muscle which helps in weight loss and enhancing muscle mass and strength. Suggested dosing is 12.5-25 mg for 4-8 weeks. Ostarine/MK 2866 Half Life MK-2886 half-life is 24 hours. So you need to taked MK 2866 once per day. Ostarine can be used for gaining as well as preserving muscle mass. For the athlete, this means it can be used in both cutting and bulking phases. The user can expect significant gains in lean body mass without unwanted water retention or fear of gynecomastia often associated with anabolic steroids. The individual will unlikely gain as much weight as he would from a cycle of Dianabol or Anadrol; however, the gains will be cleaner and easier to maintain post use. It is very common for the individual to associate all weight gain with positive gains when using certain steroids, but lean muscle gains are the only ones that count.

Minimum Order: 10 long tons