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In the downstream separation and purification process of biopharmaceuticals, chromatography is one of the indispensable separation methods. Bio-Link provides customers with 5 different chromatography solutions, including gel filtration chromatography, ion exchange chromatography, affinity chromatography , hydrophobic chromatography and multimodal chromatography. In addition, Bio- Link also produces chromatography columns and prepacked columns from laboratory to industrial grade. We focus on providing customers with high-quality products, professional solutions and comprehensive after-sales services. How To Select The Appropriate Chromatography Resin For My Own Process? To select a suitable chromatography medium and chromatography mode, we need to clarify the purpose of chromatography and the isoelectric point PI (charge property) of the target product. The PI of the target product can be obtained by calculating the target product sequence (theoretical isoelectric point), or by capillary isoelectric focusing electrophoresis (CIEF) (actual isoelectric point). Separation of substances based on the difference in charge between the target product and impurities in a buffer with a specific pH value. According to different chromatographic purposes, two modes can be selected for the ion exchange chromatography process: (1) flow-through mode: the target product does not bind to the packing material, and impurities are bound to the chromatography packing material as much as possible; (2) combined elution mode : The target product is combined with the filler, and then eluted with a certain concentration of salt. FAQs of Ion Exchange Chromatography  What is the principle of ion-exchange chromatography?  resin column chromatography is a chromatography method that separates substances according to the difference in charge properties of different biomolecules. The ion exchange chromatography medium is composed of agarose/dextran/polymer matrix coupled with ligands with positive and negative charges. The medium with negative charge is called cation exchange chromatography medium, which can bind positively charged proteins; the medium with negative charge is called anion exchange chromatography medium, which can bind negatively charged proteins.  How many chromatography resin can Bio-Link produce per year?  The chromatographic medium manufacturing facility for Bio-Link is situated in Lanzhou City, Gansu Province, and spans a total area of more than 7,000 square meters. The factory is in charge of producing purification and cell culture items such chromatography packing materials and microcarriers, with a total investment of more than 100 million yuan and close to 100 workers. The base now contains a production line for 500L and 1000L chromatography packaging, as well as a well-equipped laboratory for quality testing (which has earned ISO9001:2015 quality management system accreditation). The plant's 80,000 liters per year total capacity is envisaged. As a professional lifescience company, BioLink is committed to continuously providing customers with high-quality innovative products and solutions.

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Column chromatography is a very common separation and purification method in drug development and mass production. It is widely used in various separation and purification steps. To meet the purification needs of our biopharmaceutical customers, we have designed the BLK-BP series of columns for common biopharmaceutical tomographic applications. The column is easy to install, simple to use, safe and reliable. Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding. Features of Industrial Chromatography Column • The tube is made of glass, and the field of view is clear. It is convenient to observe the position of the bed (the bed height can be determined by comparing with the scale line on the outer wall of the tube) and the state of the glue surface. • Sanitary design, in line with GMP requirements; • Can manually adjust the height of the cylinder head and lock the sealing ring by rotating screw, easy to operate; • Easy maintenance and repair; • The side outlet is reserved at the bottom to facilitate the connection of valves and pipelines; • Level screw handle meets ergonomic requirements, easy to operate. • Optional diameter specifications: 100, 200, 300, 450 mm; • Optional height specifications: 500, 750, 950 mm; • Optional screen aperture: 10μm, 20μm As a professional lifescience company, BioLink is committed to continuously providing customers with high-quality innovative products and solutions.

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Chrom-LinX® large glass chromatography columns can be divided into two designs: single and double adjustable cylinder. The single adjustable cylinder design mainly consists of adjustable cylinder, column tube and fixed cylinder. The double adjustable cylinder design replaces the fixed cylinder with an adjustable cylinder to extend the volume range that can be loaded. Chrom-LinX® laboratory grade chromatographic column is standard with 10 μm screen (optional 5 μm screen) and is compatible with common tomographic fillers of different particle sizes. Chrom-LinX® laboratory grade chromatographic columns are made of biocompatible materials with good chemical tolerance. It is compatible with common aqueous solutions and most organic solvents, but does not tolerate chlorinated hydrocarbons, acetone and other ketones, fatty esters and phenol, etc. At the same time, it is prohibited to use under the condition of containing more than 2 M NaOH, 1 M HCl, other strong inorganic acids, 75% acetic acid solution. Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding. Features and Benefits of Chrom-LinX Laboratory Grade Empty Columns User-friendly design: Ergonomically design the components for easy grasping and handling. Clear view: Equipped with a measurement scale of glass tube for easy to predict and reach a predefined bed height and improving process reproducibility. High pressure resistance: compatible with common resins of different particle sizes allowing operation up to 20 bar* (2 MPa, 290 psi) pressure. Various sizes: Glass tubes with inner diameter (i.d.) of 10 mm, 16 mm, 26 mm or 50 mm, and bed height of 200 mm, 400 mm, 700 mm or 1000 mm provide a wide range of column volumes. High flexibility: Equipped with single/double adjustable capital for flexible expansion of column volumes. Easy to clean: Each component for easy assembling removing and cleaning. Compatibility: Supplied with tubing and connectors suitabling for a variety of common laboratory tomographic systems. *The columns withstands pressures up to 7 bar (0.7 MPa, 101.5 psi) with 50 mm inner diameter. Product Characteristics of Chrom-LinX Laboratory Grade Empty Columns Chrom-LinX® laboratory grade empty chromatography column are divided into two designs: single adjustable capital and double adjustable capital. The design of single adjustable capital mainly consists of an adjustable capital, a chromatography column tube and a fixed capital. The design of double adjustable capital replaces the fixed capital with an adjustable capital to extend the column volume (Fig 2). Chrom-LinX® laboratory grade empty chromatography columns is standard equipped with 10 μm net ring (5 μm net ring being also optional), which is compatible with common resins of different particle sizes. Chemical Resistance of Chrom-LinX Laboratory Grade Empty Columns Chrom-LinX® laboratory grade chromatography columns empty are made of biocompatible materials with good chemical tolerance. The columns can be used in aqueous solutions and almost all the organic solvents commonly used in liquid chromatography of macromolecules. The columns intolerant of chlorinated hydrocarbons, acetone and other ketones, aliphatic esters, and phenol. The columns are not allowed to use the solution containing more than 2 M NaOH, 1 M HCl, other strong mineral acids, or 75% acetic acid.

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CytoLinX® WB series single-use cell culture bags are suitable for wavy cell culture systems and are designed for common wave bags cell culture applications in biopharmaceuticals. Can be used for scientific research, process development, commercial production operation. This product is irradiation sterilization product, disposable use, for cell growth to provide a safe and suitable environment. Available in a range of sizes to support cultures from 25ml to 25L. Includes basic cell culture bag, pH&DO cell culture bag, perfusion cell culture bag, pH&DO perfusion cell culture bag. Features of CytoLinx WB Cell Culture Bags Cell Culture Media Bags • Simple installation and easy operation; • Minimize the risk of contamination and cross-contamination between samples; • Good stability, the bag is composed of multiple layers of co-extruded transparent film, excellent mechanical strength, suitable for a long time cell culture process; • High cell density; • Good biological safety, material liquid contact layer is EVA copolymer, biological inert material, to ensure process safety; • Complete verification documents; • Reduce costs; • Can be used from 10° C to 50° C; • Maximum operating pressure: 0.1 bar; • Flexible customization of pipes, joints and other components according to customer requirements; Permalife Cell Culture Bags Specifications of CytoLinX WB Cell Culture Bags CytoLinX™ WB Cell Culture Bag Components CytoLinX™ WB cell bags are made of multi-layer co-extruded film materials, the material-liquid contact layer is EVA copolymer, which is widely used in the field of biopharmaceuticals, and the outer layer is a composite material with good flexibility, strength and very low gas permeability, suitable for common cell system culture. Verify file overwriting: Aseptic test. Endotoxicity test. Completeness test. Extractable test. Chemical compatibility table. Tested on a gamma-irradiated bag, biocompatibility complies with: 1) ISO 10993-4: In vivo hemolysis study (extraction method). 2) USP87: Cytotoxicity study (extraction method). 3) USP<88> Class VI muscle implant test. 4) USP88: Study on acute intradermal injection reaction. 5)USP88: Acute systemic toxicity study. As a professional lifescience company, BioLink is committed to continuously providing customers with high-quality innovative products and solutions.

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Rmist(Tianjin) Medical Equipment Co.,Ltd is located in Jinnan Balitai Industrial Park in Tianjin of China. RMIST is a technology-based company integrating innovation, R&D, production marketing and sales. With the total capital of 20 million investment, we established the 100.000-level purification workshop of 2200 m² , and the 10.000-leve laboratory of 60 m² Our main products are Class I/ll medical devices applied in airway management such as Laryngeal masks. Endo-tracheal tubes, Endobronchial tubes and Nasopharyngeal tubes and other innovated intubations dominated by anesthesia and michanical ventilations.

Welinktech Hypodermic Needle Molds are specifically designed to produce needles for syringes that are used for various medical applications. These molds come in different shapes and sizes, ensuring precision and accuracy in the manufacturing process to guarantee that the needles are safe for medical use. TYPES OF HYPODERMIC NEEDLE MOLD Hypodermic Needle Cap Mold (14G, 16G, 17G, 18G, 19G, 20G, 21G, 22G, 23G, 24G, 25G, 26G, 27G, 28G, 29G, 30G, 31G) Hypodermic Needle Hub Mold (14G, 16G, 17G, 18G, 19G, 20G, 21G, 22G, 23G, 24G, 25G, 26G, 27G, 28G, 29G, 30G, 31G) ADVANTAGES OF HYPODERMIC NEEDLE MOLD 1. Precision and Accuracy: Hypodermic needle molds are intended to manufacture needles with specific dimensions and properties, assuring manufacturing precision. 2. Increased Efficiency: Using hypodermic needle molds may improve the efficiency and speed of the manufacturing process, lowering labor costs and turnaround time. 3. Cost-effective: The capacity of needle molds to manufacture a high volume of needles in a short length of time decreases manufacturing costs, making the production process more cost-effective. 4. Consistency: Hypodermic needle molds are designed to produce needles with uniform dimensions, resulting in consistent products that fulfill the requisite safety and quality criteria for medical applications. 5. Customizable: Needle molds can be customized to meet specific requirements for unique needles, ensuring that the final product meets the demands of the medical sector. 6. Quality Assurance: The use of needle molds in needle production ensures that the needles are of high quality and meet the necessary safety and quality standards. UNDERSTANDING THE DIFFERENCES AMONG HYPODERMIC NEEDLE MOLDS 1 The flow rate of the liquid being injected is affected by the gauge of the needle. Flow rates will be slower with smaller gauge needles than with larger gauge needles. 2 Patients are often more comfortable with smaller gauge needles since they produce less discomfort and bleeding. Bigger gauge needles cause greater discomfort and may result in more bleeding. 3 The needle gauge used will also be determined by the application. A 14G needle, for example, may be utilized for heavier fluids, but a 30G needle may be appropriate for administering insulin. 4 The design of different gauge needles can vary based on the manufacturing process. For example, thinner needles may require more precise molds and additional steps in the manufacturing process. We can offer high quality hypodermic needle manufacturing machine for sale, if you have needs, please contact us. If you are looking for reliable medical molding companies, please contact us, and we will be your best partner.

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The Welinktech Drip Chamber Assemble Machine is a state-of-the-art piece of equipment used for precisely assembling IV drip chambers. These machines automate the assembly process by using robotic arms to perform various operations, including ultrasonic welding, cutting, and assembly of drip chamber components such as the drip chamber, air vent, spike, and fluid filter. To ensure efficient and reliable production, the Welinktech Drip Chamber Assemble Machine is equipped with sensors and cameras that detect any faults in the assembled drip chambers. The machine can produce a large number of high-quality drip chambers quickly and accurately, while maintaining strict quality control standards for medical device manufacturing. SPECIFICATION OF DRIP CHAMBER ASSEMBLY MACHINE Assembly speed 5500-6000pcs/h Input power 220V50HZ Machine Size 340*390*165cm Full machine power 2.3w Weight 2000kg Atmospheric pressure 0.45-0.6MPa WHAT IS A DRIP CHAMBER ASSEMBLY MACHINE USED FOR? A drip chamber assemble machine is used in the assembly of IV drip chambers. The machine automates the process of assembling various components that form the drip chamber, including the air vent, spike, fluid filter, and drip chamber itself. The machine utilizes robotic arms, ultrasonic welding, and cutting to guarantee an efficient, consistent, and high-quality assembly process. Additionally, it is equipped with sensors and cameras that inspect the final product to ensure there are no defects, and guarantee a perfect product is produced. These machines are essential in the medical device manufacturing industry as they guarantee an efficient and accurate production of IV drip chambers. WHAT ARE THE BENEFITS OF USING A DRIP CHAMBER ASSEMBLY MACHINE? The machines' automation of the assembly process results in higher productivity and an increased capacity for output. Using these machines ensures a uniform assembly process, creating quality products consistently. By detecting defects in assembled drip chambers, these machines ensure that only flawless products are delivered. These machines reduce labor costs, resulting in an efficient production process and reduced per-unit cost. These machines minimize rejected products by ensuring proper assembly of components. Robotic arms used in these machines allow for precision assembly, ensuring that drip chambers are exactingly made. The strict healthcare standards met in building these machines guarantee the production of safe, regulatory-compliant final products. These machines can be tailored to produce various types of drip chambers suited for different medical applications. If you are looking for a reliable medical molding factory, please contact us, and we will be your best partner.

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Welinktech Disposable Syringe Mold is a high quality and precise injection mold that meets the needs of medical and healthcare applications. It has a unique design that is easy to use and allows for accurate and efficient production. The mold is crafted from durable materials and is safe and reliable for use. TYPES OF DISPOSABLE SYRINGE MOLD Three Part Syringe Plunger Mold Three Part Syringe Barrel Mold Two Part Syringe Plunger Mold Two Part Syringe Barrel Mold Syringe Gasket Mold ADVANTAGES OF DISPOSABLE SYRINGE MOLD Disposable syringe molds offer several advantages compared to their reusable counterparts: they are more cost effective, require less maintenance, and are easier to use. Additionally, disposable molds can be quickly cleaned and sterilized, eliminating the need for manual cleaning and reducing the risk of cross-contamination. Finally, due to their single-use nature, the risk of spreading disease or infection through multiple uses is greatly reduced, making them a much safer option for medical and healthcare settings. HOW TO STORE DISPOSABLE SYRINGE MOLD? 1 Disposable Syringe Mold should be stored in a clean, dry and well-ventilated environment. 2 Ensure that the temperature and humidity of the storage environment are suitable and it is away from direct sunlight. 3 Place the mold in a flat position and keep it away from sharp objects and corrosive chemicals. 4 Wrap the mold in a protective material such as cloth or plastic to prevent dust or other contaminants from affecting the mold. As one of syringe mould manufacturers, we will do our best to meet all the needs of customers. If you are looking for a reliable medical molding manufacturer, please contact us, and we will be your best partner.

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