Pharmaceutical Intermediates

Product Name: Xanthone Synonyms: 9-OXOXANTHENE;9-XANTHENONE;BENZOPHENONE OXIDE;Genicide;Xanthene, 9- Oxo-;Xanthenone;9-xanthenore;Xanthone, 99% (9-Xanthenone) Product Categories: Inhibitors;Bioactive Small Molecules;Building Blocks;C13 to C14;Carbonyl Compounds;Cell Biology;Chemical Synthesis;Hypericum perforatum (St John′;Ketones;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);s wort);X;Drug bulk Melting point  172-174 °C(lit.) Boiling point  349-350 °C730 mm Hg(lit.) density  1.1607 (rough estimate) refractive index  1.6000 (estimate) Fp  350-351°C storage temp.  Store below +30°C. form  neat Water Solubility  It is Soluble in water (partly), chloroform, hot Toluene, ether (slightly), and hot alcohol. Chemical Properties: off-white powder Uses: Acts as an inhibitor of human cancer cell lines. Definition: ChEBI: The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9. Definition A colorless crystalline organic compound found as a pigment in gentians and other flowers. It is used as an insecticide and in making dyestuffs.

Minimum Order: 10 long tons

Product Name: (Bromomethyl)cyclopropane Synonyms: CPMBr;Cyclopropylcarbinyl bromide;Bromo(cyclopropyl)methane;1- (Bromometh , yl)cyclopropane, 95+%;(Bromomethyl)cyclopropane,Cyclopropylmethyl bromide;(Bromomethyl)cyclopr;(Bromomethyl)cycl , opropane,96%;Cyclopropane Methyl Chloride Product Categories: Methyl Halides;Halides;Methyl Halides;Ring Systems;Cycloalkanes;Miscellaneous Reagents Melting point  87-90 °C Boiling point  105-107 °C(lit.) density  1.392 g/mL at 25 °C(lit.) refractive index  n20/D 1.457(lit.) Fp  107 °F storage temp.  0-6°C form  Liquid Specific Gravity 1.392 color  Clear colorless to slightly colored Water Solubility  Not miscible in water. Uses: (Bromomethyl)cyclopropane is used in the synthesis of 1,4-dienes by iron- catalyzed cross-coupling with alkenyl Grignard reagents. Description: (Bromomethyl) cyclopropane is a cyclopropane derivative. It can be used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1, 4-dienes via iron-catalyzed cross- coupling with alkenyl Grignard reagents. Chemical Properties: Colorless to yellow liquid

Minimum Order: 10 long tons

Product Name: Atropic acid Synonyms: 2-Phenylpropenoic acid;2-PHENYLPROP-2-ENOIC ACID;Ipratropium EP Impurity D;Ipratropium Bromide EP Impurity D (2-Phenyl Acrylic Acid);Ipratropium Bromide EP Impurity D;2-Phenylacrylic acid 95%;2-PHENYLACRYLIC ACID;ALPHA- PHENYLACRYLIC ACID Product Categories: Aromatics, Impurities;Pharmaceutical Intermediates Melting point  106-107° Boiling point  bp ~267° with partial decompn density  1.0061 (rough estimate) refractive index  1.5049 (estimate) pka 3.86±0.11(Predicted) Water Solubility  1.3g/L(20 ºC) Chemical Properties: White Solid Uses: Atropic acid is an Impurity of Ipratropium bromide (I740500) and Atropine Sulfate (A794625).

Minimum Order: 10 long tons

Product Name: Methoxypolyethylene glycols Synonyms: 2-ethanediyl),.alpha.-methyl-.omega.-hydroxy-Poly( , oxy-1;ETHYLENE GLYCOL 750 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 5000 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 550 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 350 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 1900 MONOMETHYL ETHER POLYMER;METHOXY POLYETHYLENE GLYCOL 750;Methoxypolyethylene glycols Product Categories: PEG;Cosmetic;Cosmetic Ingredients & Chemicals;Non-Ionic Detergents;Polydispersed PEG;construction;Detergents;Detergents N to Z;Hydroxy;Materials Science;Monofunctional PEGs;Poly(ethylene glycol) and Poly(ethylene oxide);Polymer Science;Optimization Reagents;Polymers;X-Ray Crystallography;Protein Structural Analysis;Proteomics Melting point  60-64 °C Boiling point  >200°C/760mmHg Vensity  1.094 g/mL at 25 °C Vapor density  >1 (vs air) Vapor pressure  0.05 mm Hg ( 20 °C) Refractive index  n20/D 1.459 Fp  268 °C Storage temp.  ?20°C Solubility  H2O: 50 mg/mL at 25 °C, clear, colorless Form  semisolid Specific Gravity 1.094 Color  White to pale yellow PH 5.5-7.0 (25℃, 50mg/mL in H2O) Water Solubility  Slightly miscible with water. Chemical Properties: varies from viscous liquid to white flakes, depending Uses: enteric coating controlled release and enteric release coatings

Minimum Order: 10 long tons

Product Name: 2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylidene- Synonyms: 2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylidene- Boiling point  357.1±42.0 °C(Predicted) density  1.14±0.1 g/cm3(Predicted)

Minimum Order: 10 long tons

PProduct Name: DL-Aspartic acid Synonyms: H-D-ASP-OH;H-DL-ASP-OH;DL-ASPARTIC ACID;DL-ASPARAGINIC ACID;D,L- ASP;DL-AMINOSUCCINIC ACID;DL-2-AMINOBUTANEDIOIC ACID;D-ASPARAGINIC ACID Product Categories: nutritional supplement;amino acid;Amino Acids Derivatives;aspartic acid;organic acids;pharmaceutical intermediate;Aspartic acid [Asp, D];alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids Melting point  300 °C alpha  [α]D20 0±0.3° (c=5, dil. HCl) Boiling point  245.59°C (rough estimate) density  1.6622 refractive index  1.4540 (estimate) storage temp.  Store at RT. solubility  SOLUBLE pka 2.28±0.23(Predicted) form  Crystalline Low Melting Mass color  Yellow Odor acid taste Water Solubility  SOLUBLE Chemical Properties: White crystalline powder Uses: Food additive. Uses: DL-Aspartic acid is used in studies on factors and conditions that enhance semen and sperm quality. Its conjugate base D-aspartate has potential use as a therapeutic agent in the treatment of schizophrenia-related symptoms.

Minimum Order: 10 long tons

Product Name: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Synonyms: 5-Methoxye-2-mercaplobenzinidazole;TIMTEC-BB SBB000219;5-METHOXY- 1H-BENZO[D]IMIDAZOLE-2-THI , OL;5-Methoxybenzimidazole-2-thiol;5-METHOXY-2- , THIOBENZIMIDAZOLE;5-METHOXY-2-MERCAPTOBENZIMIDAZOL , E;5-METHOXY-2- BENZIMIDAZOLETHIOL;2-MERCAPTO-5- , METHOXY-1H-BENZIMIDAZOLE Product Categories: OLED materials,pharm chemical,electronic;Aromatics;BENZIMIDAZOLE;Be , nzimidazoles;Building Blocks;Sulfur & Selenium Compounds;BUILDING BLOCKS;Imidazol&Benzimidazole;(intermediate of omeprazole);Heterocyclic Building Blocks Melting point  261-263 °C(lit.) Boiling point  309.4±44.0 °C(Predicted) density  1.2425 (rough estimate) refractive index  1.5690 (estimate) storage temp.  Refrigerator, Under Inert Atmosphere pka 10.13±0.30(Predicted) form  Powder color  Off-white to light yellow-brown Water Solubility  insoluble Sensitive  Air Sensitive Description: 2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5- methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H- benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2- bis(diphenylphosphino)ethane]-1:2

Minimum Order: 10 long tons

Product Name: Chloromethyl isopropyl carbonate Synonyms: CMIC;CHLOROMETHYL ISOPROPYL CARBONATE;I-PROPYL CHLOROMETHYL CARBONATE;Chloromethyl (1-Methylethyl) Carbonate;Chloromethyl-2-propyl carbonate;L- Propylchloromethylcarbonate;Chloro , methyl Isopropyl Carbonate (JMC-1);Carbonic acid, chloromethyl 1-methylethyl ester Product Categories: Miscellaneous Reagents;Pharmaceutical Intermediates Boiling point  66 °C(Press: 16 Torr) density  1.14 refractive index  1.4110-1.4150 storage temp.  Refrigerator, Under Inert Atmosphere Chemical Properties: Clear Colourless Liquid

Minimum Order: 10 long tons

Product Name: 4-Phenylbutyric acid Synonyms: PHENYLBUTYRIC-4 ACID;PHENYLBUTYRIC ACID;GAMMA-PHENYL-N-BUTYRIC ACID;GAMA-PHENYLBUTYRIC ACID;AKOS BBS-00003749;4-PHENYL-N-BUTYRIC ACID;4- PHENYLBUTANOIC ACID;4-PHENYLBUTYRIC ACID Product Categories: Aromatics;Intermediates & Fine Chemicals;Organic acids;Carbonyl Compounds;Carboxylic Acids;Pharmaceuticals;Pharmaceutical Raw Materials;C10 Melting point  49-51 °C(lit.) Boiling point  165 °C10 mm Hg(lit.) density  1.0326 (rough estimate) refractive index  1.5405 (estimate) Fp  >230 °F storage temp.  Store below +30°C. solubility  5.3g/l pka 4.76(at 25℃) form  Crystalline Powder color  White to slightly yellow Water Solubility  5.3 g/L at 40 ºC Chemical Properties: 4-Phenylbutyric acid is white to slightly yellowish crystalline powder Uses: A chemical chaperone involved in protein-folding disorders. Uses: 4-Phenylbutyric acid is used as organic intermediates.

Minimum Order: 10 long tons

Product Name: TETRAMETHYL-1,3-CYCLOBUTANEDIONE Synonyms: TETRAMETHYL-1,3-CYCLOBUTANEDIONE;TETRAMETHYLCYCLOB , UTANE-1,3- DIONE;TIMTEC-BB SBB008408;RARECHEM AQ C4 0041;2,2,4,4-TETRAMETHYL-1,3- CYCLOBUTANEDIONE; , DIMETHYL KETENE DIMER;1,1,3,3-Tetramethylcyclobutanedione;2,2,4,4- , Tetramethyl cyclobutane-1,3-dione Product Categories: Building Blocks;C7 to C8;Organics;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Cyclobutanes & Cyclobutenes;Simple 4-Membered Ring Compounds;C7 to C8;Carbonyl Compounds;Ketones Melting point  114-116 °C(lit.) Boiling point  95-159 °C750 mm Hg(lit.) density  1.0373 (rough estimate) refractive index  1.4580 (estimate) Fp  120-122°C/150mm solubility  It is soluble in chloroform. Chemical Properties: white crystalline powder

Minimum Order: 10 long tons

Product Name: 2-Chloro-3',4'-dihydroxyacetophenone Sy , nonyms: A-CHLORO-3',4'-DIHYDROXYACETOPHENONE;3' , ;,4'-DIHYDROXY-2-CHLORO ACETOPHENONE;3,4-DIHYDROXY-2'-CHLOROACETOP , HENONE;3,4-DIHYDROXYPHENACYL CHLORIDE;3,4-DIHYDROXY-W-CHLOROACETOPHENONE;4- , (CHLORACETAL)CATECHOL;4- (CHLOROACETYL)PYROCATE , CHOL;4-(CHLOROACETYL)CATECHOL Product Categories: Aromatics;FINE Chemical & INTERMEDIATES;Pharmaceutical Intermediates Melting point  174-176 °C(lit.) Boiling point  418.7±35.0 °C(Predicted) density  1.444±0.06 g/cm3(Predicted) storage temp.  Refrigerator solubility  Soluble in DMSO, methanol. pka 7.59±0.20(Predicted) form  neat Chemical Properties: Off-White Solid

Minimum Order: 10 long tons

Product Name: Methanesulfonic anhydride Synonyms: fonic acid, 1,1'-anhydride;METHANESULPHONIC ANHYDRIDE;METHANESULFONIC ANHYDRIDE;METHYLSULFONIC ANHYDRIDE;Mesyl anhydride;Methanesulfonic acid, anhydride;methanesulfonicacid,anhydride;Mesic anhydride Product Categories: Organic Building Blocks;Sulfonic/Sulfinic Acid Anhydrides;Sulfur Compounds Melting point  64-67 °C (lit.) Boiling point  125 °C/4 mmHg (lit.) density  1,36 g/cm3 vapor density  3.3 (vs air) refractive index  1.5300 (estimate) Fp  125°C/4mm storage temp.  Store at <= 20°C. solubility  Soluble in organic solvents. form  Powder, Crystals and/or Chunks color  White to light brown to gray Sensitive  Moisture Sensitive Chemical Properties: white to light brown to grey powder, crystals and/

Minimum Order: 10 long tons

Product Name: Methyl 5-chloro-6-methylpyrazine-2-carboxylate Synonym , s: 5-Chloro-6-methyl-2-pyrazinecarboxylic acid methyl ester;Methyl 5- chloro-6-methylpyrazine-2-carboxylate;5-Chlo , ro-6-methyl-pyrazine-2-carboxylic acid methyl ester;N-1H-BENZIMIDAZOL-4-YLFORMAMIDE;2-Pyrazineca , rboxylic acid, 5-chloro-6- methyl-, methyl ester;5-Chloro-6-methyl-2-pyrazinecarboxylic acid methyl ester fandachem;Methyl 5-chloro-6-methylpyrazine-2-carboxylate ISO 9001：2015 REACH Melting point  40-43℃ Boiling point  260℃ density  1.314 Fp  111℃ pka -3.86±0.10(Predicted)

Minimum Order: 10 long tons

Product Name: Methyl 2,5-dihydroxybenzoate Synonyms: METHYL GENTISATE;METHYL 2,5-DIHYDROXYBENZOATE;METHYL 3,6- DIHYDROXYBENZOATE;GENTISIC ACID METHYL ESTER;dihydroxybenzoic acid methyl ester;TIMTEC-BB SBB007711;RARECHEM AL BF 0043;2,5-Dihydroxybenzoic acid methyl ester Product Categories: Aromatic Esters;Acids & Esters;Phenols Melting point  86-88 °C (lit.) Boiling point  136 °C / 1mmHg density  1.354±0.06 g/cm3(Predicted) pka 9.87±0.18(Predicted) Uses methyl gentisate is also known as methyl dihydroxybenzoate. It is a skin- lightening ingredient that acts by inhibiting the melanocyte’s production of tyrosinase. It can be naturally obtained from gentian root.

Minimum Order: 10 long tons